Alternative Rule-Out Cutoffs for a Novel High-Sensitivity Cardiac Troponin I Assay in Patients With Suspected Myocardial Infarction

Myocardial Infarction

Early Rule Out of Myocardial Infarction With a Novel High-Sensitivity Cardiac Troponin T Assay

JAMA Cardiol

Thurston AJF, Tew YY, Lopez-Ayala P, Koechlin L, O'Brien R, Lynch S, Cooper JG, Fujisawa T, Bima P, McDermott M, Tuck C, Mizerska M, Highton-Williamson E, McCurrach F, Lowry MTH, Doudesis D, Anand A, Lee KK, Ferry AV, Chapman A, Newby DE, Boeddinghaus J, Mueller C, Gray AJ, Mills NL, POC-ET and APACE Investigators

doi: 10.1001/jamacardio.2026.0477

Myocardial Infarction

Comparison of the European Society of Cardiology 0/1-Hour and High-Sensitivity Troponin in the Evaluation of Patients With Suspected Acute Coronary Syndrome 0/2-or-0/3-Hour Algorithms for Rapid Myocardial Infarction Diagnosis: A Prospective Multicenter Study

J Am Coll Cardiol

Glaeser J, Lopez-Ayala P, Kellner C, Boeddinghaus J, Nestelberger T, Koechlin L, Sörensen NA, Haller PM, Bima P, Crisanti L, Spagnuolo CC, Strebel I, Hure G, Sieber S, Rubini Gimenez M, Wildi K, Wussler D, Miro O, Martin-Sanchez FJ, Keller DI, Christ M, Twerenbold R, Mahfoud F, Neumann J, Mueller C, APACE and BACC Investigators

doi: 10.1016/j.jacc.2025.12.056

Further Publications

Clinical Decisions and Outcomes After Switching High-Sensitivity Cardiac Troponin Assays in Suspected ACS: An Interrupted Time-Series Study

JAMA Cardiol

Boeddinghaus J, Li Z, Bularga A, Taggart C, Wereski R, Chapman AR, Lee KK, Tuck C, Gunn R, Jenks S, McCance K, Pattenden R, Malo J, Thurston AJF, Tew YY, McDermott M, Gray A, Cruden NLM, Anand A, Kimenai DM, Mills NL, TWITCH-ED Investigators

doi: 10.1001/jamacardio.2025.4661

Myocardial Infarction

Long forms of cardiac troponin T for myocardial infarction diagnosis: the SuperTROPO study

Eur Heart J

Teppo K, Airaksinen KEJ, Vasankari T, Linko-Parvinen A, Pallari HM, Paana T, Jaakkola S, Junes H, Salonen S, Tuominen T, Simonen S, Strandberg M, Hellman T, Wittfooth S

doi: 10.1093/eurheartj/ehaf975

Myocardial InfarctionTherapy and Intervention

Comparison of Cardiac Troponin T and I: Impact on Definitions of Perioperative Myocardial Infarction After Coronary Artery Bypass Grafting

J Am Heart Assoc

Koechlin L, Salikhanov I, Strebel I, Gahl B, Mawad B, Landert N, Vöhringer L, Reuthebuch O, Haaf P, Zellweger M, Siegemund M, Mueller C, Berdajs D

doi: 10.1161/JAHA.125.045234

Further Publications

High-sensitivity cardiac troponin I and risk of dementia: the 25-year longitudinal Whitehall II study

Eur Heart J

Chen Y, Shipley M, Anand A, Kimenai DM, Ebmeier KP, Sabia S, Singh-Manoux A, Deanfield J, Kivimaki M, Livingston G, Mills NL, Brunner EJ

doi: 10.1093/eurheartj/ehaf834

Myocardial Infarction

Causes of Myocardial Infarction in Younger Patients: Troponin-Elevation in Persons ≤65 Years Old in Olmsted County

J Am Coll Cardiol

Raphael CE, Sandoval Y, Beachey JD, Roger V, Singh M, Johnson MP, Tweet MS, Bell MR, Lerman A, Hayes SN, Holmes DR, Gersh BJ, Jaffe AS, Gulati R

doi: 10.1016/j.jacc.2025.07.012

Myocardial Infarction

The cholesterol, high-density lipoprotein, and glucose (CHG) index as a novel metabolic marker for predicting adverse outcomes in myocardial infarction survivors: insights from two large prospective cohorts

Cardiovasc Diabetol

Song Y, Chen X, Chang Z, Bian X, He J, Li B, Zheng Z, Wang C, Lin Z, Zhu C, Fu R, Dou K

doi: 10.1186/s12933-026-03104-4

Myocardial Infarction

Mineralocorticoid Receptor Antagonists in Myocardial Infarction Patients: A Systematic Review and Meta-Analysis of Randomized Trials

JACC Heart Fail

d'Entremont MA, Cheema Z, Pitt B, Kedev S, Cornel JH, Stankovic G, Moreno R, Storey R, Bossard M, Chauhan A, Montalescot G, Beygui F, Zannad F, Jolly S, Mineralocorticoid Antagonist Post Myocardial Infarction Trialist Collaboration

doi: 10.1016/j.jchf.2025.102531

Related content

Early Rule Out of Myocardial Infarction With a Novel High-Sensitivity Cardiac Troponin T Assay

Comparison of the European Society of Cardiology 0/1-Hour and High-Sensitivity Troponin in the Evaluation of Patients With Suspected Acute Coronary Syndrome 0/2-or-0/3-Hour Algorithms for Rapid Myocardial Infarction Diagnosis: A Prospective Multicenter Study

Clinical Decisions and Outcomes After Switching High-Sensitivity Cardiac Troponin Assays in Suspected ACS: An Interrupted Time-Series Study

Long forms of cardiac troponin T for myocardial infarction diagnosis: the SuperTROPO study

Comparison of Cardiac Troponin T and I: Impact on Definitions of Perioperative Myocardial Infarction After Coronary Artery Bypass Grafting

High-sensitivity cardiac troponin I and risk of dementia: the 25-year longitudinal Whitehall II study

Causes of Myocardial Infarction in Younger Patients: Troponin-Elevation in Persons ≤65 Years Old in Olmsted County

The cholesterol, high-density lipoprotein, and glucose (CHG) index as a novel metabolic marker for predicting adverse outcomes in myocardial infarction survivors: insights from two large prospective cohorts

Mineralocorticoid Receptor Antagonists in Myocardial Infarction Patients: A Systematic Review and Meta-Analysis of Randomized Trials