Cardiac Biomarkers in Patients with Asymptomatic Severe Aortic Stenosis: Analysis from the EARLY TAVR Trial

Heart, Artery and Coronary DiseasesTherapy and Intervention

ACURATE neo2 valve versus commercially available transcatheter heart valves in patients with severe aortic stenosis (ACURATE IDE): a multicentre, randomised, controlled, non-inferiority trial

Lancet

Makkar RR, Ramana RK, Gnall E, Ramlawi B, Cheng W, Diamantouros P, Potluri S, Kleinman N, Gupta A, Chakravarty T, Samy S, Rassi A, Rajagopal V, Yakubov S, Sorajja P, Patel D, Garcia S, Yadav P, Thourani V, Wang J, Rinaldi M, Kapadia S, Waksman R, Webb J, Ren CB, Gregson J, Modolo R, Sathananthan J, Reardon MJ, ACURATE IDE study investigators

doi: 10.1016/S0140-6736(25)00319-8

Heart, Artery and Coronary DiseasesTherapy and Intervention

Prognostic Value of Myocardial CT-ECV in Severe Aortic Stenosis Requiring Aortic Valve Replacement: A Systematic Review and Meta-analysis

Eur Heart J Cardiovasc Imaging

Faggiano A, Gherbesi E, Carugo S, Brusamolino M, Cozac DA, Cozza E, Savo MT, Cannata F, Guglielmo M, La Mura L, Fazzari F, Carrabba N, Conte E, Mushtaq S, Baggiano A, Guaricci AI, Pedrinelli R, Indolfi C, Sinagra G, Perrone Filardi P, Pergola V, Pontone G

doi: 10.1093/ehjci/jeae324

Heart, Artery and Coronary DiseasesTherapy and Intervention

Transcatheter or Surgical Treatment of Patients With Aortic Stenosis at Low to Intermediate Risk: An Individual Participant Data Meta-Analysis

JAMA Cardiol

Ludwig S, Klimek M, Bay B, Blankenberg S, Granada JF, Hildick-Smith D, Hudson J, Jørgensen TH, Leon MB, Magnussen C, Thiele H, Hørsted Thyregod HG, Wendler O, de Backer O, Toff WD, Ziegler A, Seiffert M

doi: 10.1001/jamacardio.2025.3403

Heart, Artery and Coronary Diseases

The Effects of Low-Dose Colchicine on the Progression of Aortic Valve Stenosis: Rationale, Design, and Baseline Characteristics of the Colchicine and Inflammation in Aortic Stenosis (CHIANTI) trial

Am Heart J

Mohammadnia N, Vestjens LTW, Craig NJ, Tijssen JGP, Knol RJJ, Lazarenko SV, Duffels MGJ, Focks JJ, Hemels MEW, Oving I, Schalkx HJ, Eikelboom JW, Cetinyurek-Yavuz A, Aarntzen EHJG, Dey D, Slomka PJ, Nijveldt R, Riksen NP, van Royen N, Honigberg MC, Dweck MR, Cornel JH, Messaoudi SE

doi: 10.1016/j.ahj.2025.07.010

Further Publications

Cardiac transthyretin amyloidosis treatment improves outcomes after aortic valve replacement for severe stenosis

Eur Heart J

Nitsche C, Dobner S, Rosenblum HR, Patel KP, Longhi S, Yilmaz A, Merlo M, Papathanasiou M, Griffin J, Oerlemans MIFJ, Gama F, Hamdan A, Kelion AD, Schuster A, Glaveckaité S, Akyol N, Porcari A, Schlender L, Capovilla T, Autherith M, Hauptmann L, Halavina K, Cavalcante JL, Fontana M, Scully PR, Moon JC, Mascherbauer J, Ristl R, Biagini E, Stortecky S, Maurer MS, Treibel TA, AS-Amyloidosis Consortium

doi: 10.1093/eurheartj/ehaf362

Atrial Fibrillation

Diabetes and Obesity and Treatment Effect of Early Rhythm Control vs Usual Care in Patients With Atrial Fibrillation: A Secondary Analysis of the EAST-AFNET 4 Randomized Clinical Trial

JAMA Cardiol

Metzner A, Willems S, Borof K, Breithardt G, Camm AJ, Crijns HJGM, Eckardt L, Fabritz L, Gessler N, Goette A, Reissmann B, Schnabel RB, Schotten U, Zapf A, Rillig A, Kirchhof P

doi: 10.1001/jamacardio.2025.2374

Heart, Artery and Coronary DiseasesTherapy and Intervention

5-Year Outcomes After Transcatheter or Surgical Aortic Valve Replacement in Low-Risk Patients With Aortic Stenosis

J Am Coll Cardiol

Forrest JK, Yakubov SJ, Deeb GM, Gada H, Mumtaz MA, Ramlawi B, Bajwa T, Crouch J, Merhi W, Wai Sang SL, Kleiman NS, Petrossian G, Robinson NB, Sorajja P, Iskander A, Berthoumieu P, Tchétché D, Feindel C, Horlick EM, Saito S, Oh JK, Jung Y, Reardon MJ, Low Risk Trial Investigators

doi: 10.1016/j.jacc.2025.03.004

Cardiac Arrest or Death

Effects of very early hyperoxemia on neurologic outcome after out-of-hospital cardiac arrest: A secondary analysis of the TTM-2 trial

Resuscitation

Sanfilippo F, Uryga A, Santonocito C, Jakobsen JC, Lilja G, Friberg H, Wendel-Garcia PD, Young PJ, Eastwood G, Chew MS, Unden J, Thomas M, Grejs AM, Wise MP, Lundin A, Hollenberg J, Hammond N, Saxena M, Martin A, Bánszky R, Taccone FS, Dankiewicz J, Nielsen N, Ebner F, BeloholaveK J, Hanggi M, Montagnani L, Patroniti N, Robba C, TTM-2 investigators

doi: 10.1016/j.resuscitation.2024.110460

Myocardial Infarction

Early anti-inflammatory therapy in acute myocardial infarction: A network meta-analysis of timing-dependent effects in 23 randomized trials and 28,220 patients

Atherosclerosis

Rivero-Santana B, Saldaña-García J, Jurado-Román A, Cantolla-Pablo P, Gil-Fernández M, López-Sendón J, Tardif JC, Moreno R, Fernández-Velasco M

doi: 10.1016/j.atherosclerosis.2025.120443

Related content

ACURATE neo2 valve versus commercially available transcatheter heart valves in patients with severe aortic stenosis (ACURATE IDE): a multicentre, randomised, controlled, non-inferiority trial

Prognostic Value of Myocardial CT-ECV in Severe Aortic Stenosis Requiring Aortic Valve Replacement: A Systematic Review and Meta-analysis

Transcatheter or Surgical Treatment of Patients With Aortic Stenosis at Low to Intermediate Risk: An Individual Participant Data Meta-Analysis

The Effects of Low-Dose Colchicine on the Progression of Aortic Valve Stenosis: Rationale, Design, and Baseline Characteristics of the Colchicine and Inflammation in Aortic Stenosis (CHIANTI) trial

Cardiac transthyretin amyloidosis treatment improves outcomes after aortic valve replacement for severe stenosis

Diabetes and Obesity and Treatment Effect of Early Rhythm Control vs Usual Care in Patients With Atrial Fibrillation: A Secondary Analysis of the EAST-AFNET 4 Randomized Clinical Trial

5-Year Outcomes After Transcatheter or Surgical Aortic Valve Replacement in Low-Risk Patients With Aortic Stenosis

Effects of very early hyperoxemia on neurologic outcome after out-of-hospital cardiac arrest: A secondary analysis of the TTM-2 trial

Early anti-inflammatory therapy in acute myocardial infarction: A network meta-analysis of timing-dependent effects in 23 randomized trials and 28,220 patients