Design and rationale of A Multicenter Paramedic randomized trial of noradrenaline versus adrenaline in the initial management of patients with cardiogenic shock - The PANDA trial - Articles - Cardiovascular

Atrial Fibrillation

Left atrial appendage occlusion versus NOACs in patients with atrial fibrillation: Rationale and design of the CATALYST Trial

Am Heart J

Reddy VY, Hylek E, Camm AJ, Halperin JL, Diener HC, Thaler D, Schmidt B, Hara H, Huisman MV, Price MJ, Lakkireddy D, Gage R, Zhao H, Jensen TP, Quintana M, Windecker S

doi: 10.1016/j.ahj.2026.107367

Further Publications

Systolic Blood Pressure and Microaxial Flow Pump-Associated Survival in Infarct-Related Cardiogenic Shock: A Post Hoc Analysis of the DanGer Shock Randomized Clinical Trial

JAMA Cardiol

Mikkelsen AD, Beske RP, Jensen LO, Eiskjær H, Mangner N, Polzin A, Schulze C, Skurk C, Nordbeck P, Schrage B, Panoulas V, Zimmer S, Schäfer A, Engstrøm T, Holmvang L, Frydland M, Junker AB, Schmidt H, Udesen NLJ, Wachtell K, Terkelsen CJ, Linke A, Kjærgaard J, Møller JE, Hassager C, DanGer Shock Investigators

doi: 10.1001/jamacardio.2025.3337

Heart FailureFurther Publications

Randomized investigation of heart failure therapy in patients with advanced cancer at risk of cardiac wasting: Rationale and design of the EMPATICC trial

Eur J Heart Fail

Anker MS, Mahabadi AA, Totzeck M, Tewes M, Mincu R, Khan MS, Butler J, Keller U, Ahn J, Bullinger L, Modest DP, Landmesser U, Lehmann LH, Bercker S, Laufs U, Böhm M, Merkely B, Diek M, Heise T, Hellmich M, Placzek M, Friede T, Anker SD, Rassaf T

doi: 10.1002/ejhf.3799

Atrial Fibrillation

Integrated Care Management for Older Multimorbid Patients with Atrial Fibrillation: Rationale, Design and Baseline Characteristics for the Atrial Fibrillation Integrated Approach in Frail, Multimorbid and Polymedicated Older People (AFFIRMO) trial

Am Heart J

Proietti M, Lip GYH, Ainsworth J, Dan GA, Frost L, Graffigna G, Lucci D, Marin F, Potpara TS, Sanaullah A, Tokmakova M, Johnsen SP, Maggioni AP, AFFIRMO Study Investigators and Consortium

doi: 10.1016/j.ahj.2026.107356

Myocardial Infarction

Selective C-reactive protein apheresis in ST-elevation myocardial infarction: Design and rationale of the randomized CRP-STEMI trial

Am Heart J

Reinstadler SJ, Kronbichler A, Reindl M, Tiller C, Holzknecht M, Oberhollenzer F, Kaser A, Gauckler P, Stiermaier T, Feistritzer HJ, Mayr A, Gizewski ER, Rezar R, Bugger H, Eller K, Eitel I, Schneider S, Mayer G, Thiele H, Bauer A, Metzler B, Lechner I, CRP-STEMI Investigators

doi: 10.1016/j.ahj.2025.07.067

Heart Failure

Dapagliflozin in Patients Hospitalized for Heart Failure: Primary Results of the DAPA ACT HF-TIMI 68 Randomized Clinical Trial and Meta-Analysis of Sodium-Glucose Cotransporter-2 Inhibitors in Patients Hospitalized for Heart Failure

Circulation

Berg DD, Patel SM, Haller PM, Cange AL, Palazzolo MG, Bellavia A, Kuder JF, Desai AS, Inzucchi SE, McMurray JJV, O'Meara E, Verma S, Bělohlávek J, Drożdż J, Merkely B, Ogunniyi MO, Drasnar T, Izzo JL, Sarman B, McGinty JE, Ramanathan K, Mulkay AJ, Przybylski A, Ruff CT, O'Donoghue ML, Murphy SA, Sabatine MS, Wiviott SD, DAPA ACT HF-TIMI 68 Trial Committees and Investigators

doi: 10.1161/CIRCULATIONAHA.125.076575

Heart Failure

Intravenous ferric carboxymaltose in patients with heart failure and iron deficiency: a systematic review and meta-analysis of randomized controlled trials with trial sequential analysis

ESC Heart Fail

Ahmed M, Zulfiqar E, Hashmi TM, Zia R, Ashraf H, Naveed MA, Ahmed R, Rana JS, Ahmed F, Greene SJ, Fudim M, Mentz RJ, Fonarow GC

doi: 10.1093/eschf/xvaf018

Further Publications

A Nationwide Factorial Randomized Trial of Electronic Nudges to Patients with Chronic Kidney Disease and Their General Practices for Increasing Guideline-Directed Medical Therapy: The NUDGE-CKD Trial

Circulation

Skaarup KG, Johansen ND, Brandi L, Lindhardt MK, Bech JN, Svensson M, Kristensen T, Thuesen AD, Knudsen MG, Kampman JD, Hornnum M, Ørts B, Modin D, Lassen MCH, Janstrup KH, Claggett BL, Vaduganathan M, Bhatt AS, Van Spall HGC, Jensen JUS, Zannad F, Solomon SD, Møller A, Borg R, Birn H, Hansen D, Biering-Sørensen T

doi: 10.1161/CIRCULATIONAHA.125.075403

Myocardial Infarction

Myocarditis-Associated Cardiogenic Shock: A Nationwide Multicenter Study

J Am Heart Assoc

El Zarif T, Ambrosini AP, Shahu A, Shen M, Gastanadui MG, Safiriyu I, Guha A, Jacobs M, Ali T, Kwan JM, Hull SC, Baldassarre L, Elliott Miller P

doi: 10.1161/JAHA.125.042850

Related content

Left atrial appendage occlusion versus NOACs in patients with atrial fibrillation: Rationale and design of the CATALYST Trial

Systolic Blood Pressure and Microaxial Flow Pump-Associated Survival in Infarct-Related Cardiogenic Shock: A Post Hoc Analysis of the DanGer Shock Randomized Clinical Trial

Randomized investigation of heart failure therapy in patients with advanced cancer at risk of cardiac wasting: Rationale and design of the EMPATICC trial

Integrated Care Management for Older Multimorbid Patients with Atrial Fibrillation: Rationale, Design and Baseline Characteristics for the Atrial Fibrillation Integrated Approach in Frail, Multimorbid and Polymedicated Older People (AFFIRMO) trial

Selective C-reactive protein apheresis in ST-elevation myocardial infarction: Design and rationale of the randomized CRP-STEMI trial

Dapagliflozin in Patients Hospitalized for Heart Failure: Primary Results of the DAPA ACT HF-TIMI 68 Randomized Clinical Trial and Meta-Analysis of Sodium-Glucose Cotransporter-2 Inhibitors in Patients Hospitalized for Heart Failure

Intravenous ferric carboxymaltose in patients with heart failure and iron deficiency: a systematic review and meta-analysis of randomized controlled trials with trial sequential analysis

A Nationwide Factorial Randomized Trial of Electronic Nudges to Patients with Chronic Kidney Disease and Their General Practices for Increasing Guideline-Directed Medical Therapy: The NUDGE-CKD Trial

Myocarditis-Associated Cardiogenic Shock: A Nationwide Multicenter Study