Sex-Related Differences in the Management and Outcomes of Patients Across the Spectrum of Aortic Stenosis

Heart, Artery and Coronary Diseases

Sex Differences in Left Ventricular Remodeling for Risk Stratification of Patients With Aortic Regurgitation

JAMA Cardiol

Lopez Santi P, Fortuni F, Bernard J, Sarrazyn C, Chua AP, Butcher SC, Meucci MC, Zhang J, Enache R, Tay E, Bergeron A, Yiu KH, Clavel MA, Pibarot P, Bax JJ, Ajmone Marsan N

doi: 10.1001/jamacardio.2025.5249

Heart, Artery and Coronary DiseasesTherapy and Intervention

Sex-specific outcomes after transcatheter or surgical treatment of aortic valve stenosis: the DEDICATE-DZHK6 trial

Eur Heart J

Bleiziffer S, Leuschner F, Rudolph TK, Vonthein R, Meyer AL, Haeusler KG, Hofmann U, Gorski A, Hagendorff A, Kim WK, Baumgartner H, Borger MA, Choi YH, Cremer J, Falk V, Frey N, Hagl C, König IR, Landmesser U, Massberg S, Reichenspurner H, Renker M, Thiele H, Walther T, Ziegler A, Blankenberg S, Dreger H, Arif R, Unbehaun A, Seiffert M, DEDICATE Study Investigators

doi: 10.1093/eurheartj/ehaf519

Further Publications

Myocardial Fibrosis and Early Intervention in Asymptomatic Patients With Severe Aortic Stenosis: Insights From the EVOLVED Randomized Clinical Trial

JAMA Cardiol

Craig NJ, Loganath K, Everett RJ, Bing R, Ramtoola T, Tsampasian V, Molek P, Botezatu S, Aslam S, MacGillivray T, Tuck CE, Rayson P, Calvert PA, Berry C, Chin CWL, Hillis GS, Fairbairn T, Greenwood JP, Steeds R, Leslie SJ, Lang CC, Bucciarelli-Ducci C, Joshi NV, Kunadian V, Prendergast B, Mills NL, Vassiliou VS, Dungu JN, Hothi SS, Boon N, Prasad SK, Keenan NG, Dawson D, Motwani M, Miller CA, Rajani R, Ripley DP, Treibel TA, McCann GP, Singh A, Newby DE, Dweck MR, EVOLVED investigators

doi: 10.1001/jamacardio.2026.0654

Cardiac Arrest or Death

Sex differences in out-of-hospital cardiac arrest across age groups

Heart

Lavignasse D, Menant E, Sideris G, Lemoine S, Bougouin W, Beganton F, Jabre P, Loeb T, Agostinucci JM, Lecarpentier E, Jost D, Cariou A, Empana JP, Jouven X

doi: 10.1136/heartjnl-2025-326987

Heart, Artery and Coronary Diseases

Proactive Management and Treatment of Aortic Stenosis: An International Expert Perspective

J Am Coll Cardiol

Cook CM, Pibarot P, Tarantini G, Généreux P, Delgado V, Hayashida K, Parma R, Kaneko T, Rudolph TK, Cavalcante JL, Wood DA, Bax JJ, Pilgrim T, Saia F, Vemulapalli S, Pellikka PA, Iung B, Guibone K, Dweck MR, Eltchaninoff H, Ailawadi G, Lam SC, Poon K, Unbehaun A, Schwartz A, Joner M, Prendergast B, Mack M, Hahn RT, Windecker S, Leon MB, Lindman BR

doi: 10.1016/j.jacc.2025.10.074

Further Publications

Cardiac transthyretin amyloidosis treatment improves outcomes after aortic valve replacement for severe stenosis

Eur Heart J

Nitsche C, Dobner S, Rosenblum HR, Patel KP, Longhi S, Yilmaz A, Merlo M, Papathanasiou M, Griffin J, Oerlemans MIFJ, Gama F, Hamdan A, Kelion AD, Schuster A, Glaveckaité S, Akyol N, Porcari A, Schlender L, Capovilla T, Autherith M, Hauptmann L, Halavina K, Cavalcante JL, Fontana M, Scully PR, Moon JC, Mascherbauer J, Ristl R, Biagini E, Stortecky S, Maurer MS, Treibel TA, AS-Amyloidosis Consortium

doi: 10.1093/eurheartj/ehaf362

Heart Failure

Effects of semaglutide in obesity-related heart failure with preserved ejection fraction across the age spectrum: Findings from the STEP-HFpEF programme

Eur J Heart Fail

Pandey A, Moroney M, Verma S, Borlaug BA, Butler J, Davies MJ, Kitzman DW, Shah SJ, Petrie MC, Rönnbäck C, Domdey A, Rasmussen S, Chinnakondepalli KM, Patel S, Kosiborod MN

doi: 10.1002/ejhf.70049

Heart, Artery and Coronary DiseasesTherapy and Intervention

Surgical Versus Transcatheter Aortic Valve Replacement in Patients Aged >60 Years With Bicuspid Valve Stenosis: A Time-to-Event Data Meta-Analysis

J Am Heart Assoc

Moscarelli M, Lancellotti P, Athanasiou T, Casula R, Pernice V, Zaccone G, Nguyen Trung ML, Giannini F, Speziale G, Gaudino M, Fattouch K

doi: 10.1161/JAHA.125.046556

Heart, Artery and Coronary DiseasesTherapy and Intervention

ACURATE neo2 valve versus commercially available transcatheter heart valves in patients with severe aortic stenosis (ACURATE IDE): a multicentre, randomised, controlled, non-inferiority trial

Lancet

Makkar RR, Ramana RK, Gnall E, Ramlawi B, Cheng W, Diamantouros P, Potluri S, Kleinman N, Gupta A, Chakravarty T, Samy S, Rassi A, Rajagopal V, Yakubov S, Sorajja P, Patel D, Garcia S, Yadav P, Thourani V, Wang J, Rinaldi M, Kapadia S, Waksman R, Webb J, Ren CB, Gregson J, Modolo R, Sathananthan J, Reardon MJ, ACURATE IDE study investigators

doi: 10.1016/S0140-6736(25)00319-8

Related content

Sex Differences in Left Ventricular Remodeling for Risk Stratification of Patients With Aortic Regurgitation

Sex-specific outcomes after transcatheter or surgical treatment of aortic valve stenosis: the DEDICATE-DZHK6 trial

Myocardial Fibrosis and Early Intervention in Asymptomatic Patients With Severe Aortic Stenosis: Insights From the EVOLVED Randomized Clinical Trial

Sex differences in out-of-hospital cardiac arrest across age groups

Proactive Management and Treatment of Aortic Stenosis: An International Expert Perspective

Cardiac transthyretin amyloidosis treatment improves outcomes after aortic valve replacement for severe stenosis

Effects of semaglutide in obesity-related heart failure with preserved ejection fraction across the age spectrum: Findings from the STEP-HFpEF programme

Surgical Versus Transcatheter Aortic Valve Replacement in Patients Aged >60 Years With Bicuspid Valve Stenosis: A Time-to-Event Data Meta-Analysis

ACURATE neo2 valve versus commercially available transcatheter heart valves in patients with severe aortic stenosis (ACURATE IDE): a multicentre, randomised, controlled, non-inferiority trial