ROBIN: A unified nanopore-based assay integrating intraoperative methylome classification and next-day comprehensive profiling for ultra-rapid tumor diagnosis

Central Nervous System Tumors

Streamlined intraoperative brain tumor classification and molecular subtyping in stereotactic biopsies using stimulated Raman histology and deep learning

Clin Cancer Res

Reinecke D, Ruess D, Meissner AK, Fürtjes G, von Spreckelsen N, Ion-Margineau A, Khalid F, Blau T, Stehle T, Al-Shughri A, Büttner R, Goldbrunner R, Ruge MI, Neuschmelting V

doi: 10.1158/1078-0432.CCR-23-3842

Further Publications

Comprehensive Genome Profiling for Treatment Decisions in Patients with Metastatic Tumors: Real-World Evidence Meta-Analysis and Registry Data Implementation

J Natl Cancer Inst

Zerdes I, Filis P, Fountoukidis G, El-Naggar AI, Kalofonou F, D'Alessio A, Pouptsis A, Foukakis T, Pentheroudakis G, Ahlgren J, Smith D, Valachis A

doi: 10.1093/jnci/djaf015

Genitourinary Cancer

Olanzapine combined with standard antiemetics for the prevention of nausea and vomiting in patients with germ cell tumor undergoing a 5-day cisplatin-based chemotherapy (NAVIGATE study)： A phase III crossover trial

Eur J Cancer

Zhang L, Chen M, Zhou Q, Xue C, Huang R, Diao X, Li J, Peng J, Zheng Q, Ni M, Zhou L, Wang D, Li H, Yang W, Dun S, Liu Z, Wang Y, Shi Y, An X

doi: 10.1016/j.ejca.2025.115437

Further Publications

Clinical and molecular risk factors in extracranial malignant rhabdoid tumors - Towards an integrated model of high-risk tumors

Clin Cancer Res

Fincke VE, Steinbügl M, Chun HE, Nemes K, Mucha M, Loßner M, Dorn F, Gastberger K, Bühner S, Sill M, Kröncke T, Siebert R, Melchior P, Furtwängler R, Schlesner M, Vokuhl C, Rocken C, Johann PD, Frühwald MC

doi: 10.1158/1078-0432.CCR-23-3489

Lung, Respiratory and Thoracic Cancer

HIV Impairs Immune Responses to Tumor Neoepitopes Without Altering Mutational Profiles in Non-Small Cell Lung Cancer

J Thorac Oncol

Abbar B, Labreche K, Cadranel J, Veyri M, Morin V, Thiam FS, Desire N, Baron M, Guillerm E, Perrier A, Fallet V, Maitre T, Canellas A, Tarantino N, Mze O, Samri A, Dejancourt L, Nakid-Cordero C, Vozy A, Picca A, Touat M, Guihot A, Chouaid C, Mokhtari K, Bielle F, Brocheriou I, Rouvier P, Rodenas Osorio A, Buob D, Bouzidi A, Marie Y, Assouad J, Boelle PY, Coulet F, Vieillard V, Spano JP, Autran B

doi: 10.1016/j.jtho.2025.02.001

Lymphoma

Circulating Tumor DNA Sequencing for Biologic Classification and Individualized Risk Stratification in Patients With Hodgkin Lymphoma

J Clin Oncol

Heger JM, Mammadova L, Mattlener J, Sobesky S, Cirillo M, Altmüller J, Kirst E, Reinke S, Klapper W, Bröckelmann PJ, Ferdinandus J, Kaul H, Schneider G, Schneider J, Schleifenbaum JK, Ullrich RT, Freihammer M, Awerkiew S, Lohmann M, Klein F, Nürnberg P, Hallek M, Rossi D, Mauz-Körholz C, Gattenlöhner S, Bräuninger A, Borchmann P, von Tresckow B, Borchmann S

doi: 10.1200/JCO.23.01867

Head and Neck Cancer

Direct Comparison of Alternative Blood-Based Approaches for Early Detection and Diagnosis of HPV-Associated Head and Neck Cancers

Clin Cancer Res

Bryan ME, Aye L, Das D, Hirayama S, Al-Inaya Y, Mendel J, Naegele S, Efthymiou V, Alzumaili B, Faquin WC, Sadow PM, Lin D, Varvares MA, Feng AL, Deschler DG, Chan AW, Paly J, Park JC, Roberts T, Merkin R, Mishra SK, Kröller L, Michels B, Iafrate AJ, Wirth LJ, Adalsteinsson VA, Crowson M, Waterboer T, Mirabello L, Lawrence MS, Guan Z, Fisch AS, Richmon JD, Faden DL

doi: 10.1158/1078-0432.CCR-24-2525

Lung, Respiratory and Thoracic Cancer

Comparative validation of nodal classifications in resected non-small cell lung cancer based on the anatomical location and number of involved stations

Lung Cancer

Isaka M, Notsu A, Kojima H, Konno H, Katsumata S, Kawata T, Endo M, Ohde Y

doi: 10.1016/j.lungcan.2025.108511

Gastrointestinal Cancer

A tumor-naive ctDNA assay detects minimal residual disease in resected stage II or III colorectal cancer and predicts recurrence: subset analysis from the GALAXY study in CIRCULATE-Japan

Clin Cancer Res

Nakamura Y, Kaneva K, Lo C, Neems D, Freaney JE, Boulos H, Hyun SW, Islam F, Yamada-Hanff J, Driessen TM, Sonnenschein A, DeSantis DF, Kotani D, Watanabe J, Kotaka M, Mishima S, Bando H, Yamazaki K, Taniguchi H, Takemasa I, Kato T, Sangli C, Tell R, Blidner R, Yoshino T, Sasser K, Oki E, Nimeiri H

doi: 10.1158/1078-0432.CCR-24-2396

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Streamlined intraoperative brain tumor classification and molecular subtyping in stereotactic biopsies using stimulated Raman histology and deep learning

Comprehensive Genome Profiling for Treatment Decisions in Patients with Metastatic Tumors: Real-World Evidence Meta-Analysis and Registry Data Implementation

Olanzapine combined with standard antiemetics for the prevention of nausea and vomiting in patients with germ cell tumor undergoing a 5-day cisplatin-based chemotherapy (NAVIGATE study)： A phase III crossover trial

Clinical and molecular risk factors in extracranial malignant rhabdoid tumors - Towards an integrated model of high-risk tumors

HIV Impairs Immune Responses to Tumor Neoepitopes Without Altering Mutational Profiles in Non-Small Cell Lung Cancer

Circulating Tumor DNA Sequencing for Biologic Classification and Individualized Risk Stratification in Patients With Hodgkin Lymphoma

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A tumor-naive ctDNA assay detects minimal residual disease in resected stage II or III colorectal cancer and predicts recurrence: subset analysis from the GALAXY study in CIRCULATE-Japan