Assessing the Fragility of Statistically Significant Outcomes in Randomised Controlled Trials of Minimally Invasive Glaucoma Surgery (MIGS)

Lenses

Efficacy of spectacle lenses for myopia control: a meta-analysis of randomised controlled trials

Br J Ophthalmol

D'Andrea L, Rinaldi M, Piscopo R, Iorio F, La Padula S, Maqsood S, Elalfy M, Melenzane A, Confalonieri F, Ozkan O, Utine CA, Costagliola C

doi: 10.1136/bjo-2025-327629

Glaucoma and Ocular PressureSurgery and InterventionUveitis

The rate of failure of trabeculectomy and tube shunt surgery in eyes with uveitic glaucoma and ocular hypertension: The purpose of this study is to look at the outcomes of trabeculectomy and tube shunt surgery in a large cohort of patients with uveitis

Ophthalmol Glaucoma

Groth SL, Newcomb CW, Yang W, Payal A, Begum H, Khachatryan N, Kaçmaz RO, Dreger KA, Rosenbaum JT, Sen HN, Suhler EB, Thorne JE, Bhatt NP, Foster CS, Jabs DA, Levy-Clarke GA, Buchanich JM, Ying GS, Kempen JH, Gangaputra S, Systemic Immunosuppressive Therapy for Eye Diseases (SITE) Cohort Study Research Group

doi: 10.1016/j.ogla.2025.05.004

Lenses

Effect of daily disposable Defocus Incorporated Soft Contact lens on myopia control: a 1-year multicentre randomised controlled trial

Br J Ophthalmol

Liu L, Wang J, Tse DY, Zuo B, Song D, Du B, Chen Z, To CH, Chun RKM, Jiang J, Wei R

doi: 10.1136/bjo-2025-327471

Lenses

Atropine and Spectacle lens Combination Treatment (ASPECT): 12-month results of a randomised controlled trial for myopia control using a combination of Defocus Incorporated Multiple Segments (DIMS) lenses and 0.025% atropine

Br J Ophthalmol

Guemes-Villahoz N, Talavero González P, Porras-Ángel P, Bella-Gala R, Ruiz-Pomeda A, Martin-Garcia B, Hernandez-Garcia E, Gomez de Liaño N, Shah R, Garcia-Feijoo J, Gomez-de-Liaño R

doi: 10.1136/bjo-2024-326852

Surgery and Intervention

Risk factors for failure in minimally invasive bleb surgery: a systematic review

Am J Ophthalmol

Jung M, Kong YZ, Ansari AS, Lawlor M, Tan JCK

doi: 10.1016/j.ajo.2025.11.045

Retinal Diseases

Intravenous alteplase versus oral aspirin for acute central retinal artery occlusion within 4·5 h of severe vision loss (THEIA): a multicentre, double-dummy, patient-blinded and assessor-blinded, randomised, controlled, phase 3 trial

Lancet Neurol

Préterre C, Gaultier A, Obadia M, Vignal C, Mourand I, Plat J, Sablot D, Gaudron M, Rodier G, Godeneche G, Urbanczyk C, Marc G, Massardier E, Adam S, Boulanger M, Marcel S, Mechtouff L, Ronzière T, Calvière L, Godard-Ducceschi S, Barbin L, Lebranchu P, Guillon B, THEIA collaborators

doi: 10.1016/S1474-4422(25)00308-4

Further Publications

3-year results of 0.01% and 0.1% loading dose atropine treatment including washout in Danish children with myopia: a placebo-controlled, randomised clinical trial

Br J Ophthalmol

Hansen N, Hvid-Hansen A, Møller F, Bek T, Larsen D, Jacobsen N, Kessel L

doi: 10.1136/bjo-2024-326918

Further Publications

The Effect of Metagenomic Sequencing on Patient Clinical Outcomes for Intraocular Infections: A Multicenter Randomized Controlled Trial

Am J Ophthalmol

Shantha JG, Moussa K, Laovirojjanakul W, Yeh S, Tsui E, Chen JL, Vitale AT, Shakoor A, Larochelle M, Niemeyer K, Mentreddy A, Livnat I, Safo M, Ao W, Choo C, Yan D, Zhong L, Chen C, Da Silva K, Reddy AK, Lee J, Sura A, Crowell EL, Qian Y, Sharon Y, Hinterwirth A, Porco T, Arnold BF, Gonzales J, Acharya NR, Lietman TM, Doan T, OPTICS Study Group

doi: 10.1016/j.ajo.2025.07.003

Glaucoma and Ocular PressureCataracts

Two-Year Outcomes of Phacogoniotomy vs Phacotrabeculectomy for Advanced Primary Angle-Closure Glaucoma With Cataract: A Noninferiority Randomized Clinical Trial

JAMA Ophthalmol

Song Y, Fan S, Tang L, Lin F, Li F, Lv A, Li X, Wen T, Lu L, Xiao M, Xie L, Zhu X, Tang G, Zhang H, Yan X, Yuan H, Song W, Yang Y, Xu J, Zhou F, Wang Z, Jin L, Liang X, Zhou M, Zhao X, Chen W, Park KH, Barton K, Aung T, Tham CC, Lam DSC, Weinreb RN, Wang N, Zhang X, PVP Study Group

doi: 10.1001/jamaophthalmol.2025.0685

Related content

Efficacy of spectacle lenses for myopia control: a meta-analysis of randomised controlled trials

The rate of failure of trabeculectomy and tube shunt surgery in eyes with uveitic glaucoma and ocular hypertension: The purpose of this study is to look at the outcomes of trabeculectomy and tube shunt surgery in a large cohort of patients with uveitis

Effect of daily disposable Defocus Incorporated Soft Contact lens on myopia control: a 1-year multicentre randomised controlled trial

Atropine and Spectacle lens Combination Treatment (ASPECT): 12-month results of a randomised controlled trial for myopia control using a combination of Defocus Incorporated Multiple Segments (DIMS) lenses and 0.025% atropine

Risk factors for failure in minimally invasive bleb surgery: a systematic review

Intravenous alteplase versus oral aspirin for acute central retinal artery occlusion within 4·5 h of severe vision loss (THEIA): a multicentre, double-dummy, patient-blinded and assessor-blinded, randomised, controlled, phase 3 trial

3-year results of 0.01% and 0.1% loading dose atropine treatment including washout in Danish children with myopia: a placebo-controlled, randomised clinical trial

The Effect of Metagenomic Sequencing on Patient Clinical Outcomes for Intraocular Infections: A Multicenter Randomized Controlled Trial

Two-Year Outcomes of Phacogoniotomy vs Phacotrabeculectomy for Advanced Primary Angle-Closure Glaucoma With Cataract: A Noninferiority Randomized Clinical Trial