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Comparative effectiveness of azithromycin versus roflumilast in patients with chronic obstructive pulmonary disease: emulated target trial
COPD
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COPD
Summary of Research: Ensifentrine, a Novel Phosphodiesterase 3 and 4 Inhibitor for the Treatment of Chronic Obstructive Pulmonary Disease: Randomized, Double-Blind, Placebo-Controlled, Multicenter Phase III Trials (the ENHANCE Trials)
★ 2
Recommended by
Dr. med. Martin Frey, Faculty Member
★ 2
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Dr Marcus Hesse, Faculty Member
Adv Ther
Anzueto A, Barjaktarevic IZ, Siler TM, Rheault T, Rickard K, O'Donovan K, Sciurba F
doi: 10.1007/s12325-026-03514-6
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COPD
Biological Therapy for Chronic Obstructive Pulmonary Disease (COPD): Effectiveness and Safety
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★ 2
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Dr Marcus Hesse, Faculty Member
Respir Med
García Morales OM, Díaz L, Auladell-Rispau A, Poloni D, Torres-López LA, Cuchi GU, Rojas-Reyes MX
doi: 10.1016/j.rmed.2026.108815
COPD
Non-Pharmacological Interventions for Fatigue in Patients with Chronic Obstructive Pulmonary Disease: a Systematic Review and Network Meta-Analysis
Respir Med
Zhang X, Xue J, Chang Y, Zhang R, Zhao J, Li X, Lu H, Jiang X, Yu F, Yang P
doi: 10.1016/j.rmed.2025.108409
COPD
A phase 2a, double-blind, randomised, placebo-controlled trial of the myeloperoxidase inhibitor, mitiperstat, in participants with chronic obstructive pulmonary disease
Eur Respir J
Saralaya D, Mustapa MN, Ferreira J, Kocks JWH, Brailsford W, Rosengren S, Spata E, Belvisi MG, Leander J, Riff C, De Palo G, Windgassen D, Chalmers JD, Russell REK, Hurst JR, Śmiałowski A, Hughes R
doi: 10.1183/13993003.02567-2025
Further Publications
The safety and efficacy of secondary spontaneous pneumothorax surgery: Especially in interstitial lung disease and chronic obstructive pulmonary disease
Eur J Cardiothorac Surg
Adachi T, Omasa M, Takehara R, Nakanishi T, Motoyama H
doi: 10.1093/ejcts/ezaf410
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Respiratory Tract Infection
Dupilumab versus omalizumab in patients with chronic rhinosinusitis with nasal polyps and coexisting asthma (EVEREST): a multicentre, randomised, double-blind, head-to-head phase 4 trial
★ 3
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Dr. med. Martin Frey, Faculty Member
★ 3
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Dr Marcus Hesse, Faculty Member
Lancet Respir Med
De Corso E, Canonica GW, Heffler E, Springer M, Grzegorzek T, Viana M, Horváth Z, Mullol J, Gevaert P, Michel J, Peters AT, Wagenmann M, Zaghloul S, Zhang M, Corbett M, Nash S, Angello JT, Radwan A, Deniz Y, Martin A, Hellings PW
doi: 10.1016/S2213-2600(25)00287-5
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Pulmonary Hypertension
Pretreatment with mono or dual PH-targeted medical therapy in patients undergoing balloon pulmonary angioplasty: effect on complications and clinical outcomes
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Chest
Staal DP, Lely RY, Breuning A, van Thor MCJ, Peper J, Nossent EJ, van Kuijk JP, Aman J, van den Heuvel D, Van Es J, Vonk-Noordegraaf A, Boerman S, Bogaard HJ, Mager JJ, Beijk MAM, Post MC
doi: 10.1016/j.chest.2026.04.048
Lung Cancer
Ivonescimab plus chemotherapy versus placebo plus chemotherapy in patients with advanced EGFR-mutated non-small-cell lung cancer after disease progression on EGFR tyrosine kinase inhibitor therapy (HARMONi): a multicentre, randomised, double-blind, phase 3 trial
Lancet Oncol
Le X, Passaro A, Zhao Y, Huang Y, Laskin J, Rodriguez-Abreu D, Calles A, Bazhenova L, Lo Russo G, Leighl NB, Cappuzzo F, Girard N, Popat S, Fang W, Luo Y, Li W, He Z, Zhao H, Li M, Song Q, Zhao H, El Darsa H, Monnet I, Cobo Dols M, García Campelo R, Jotte R, Berz D, Spira A, Pérol M, Nagasaka M, West H, Styles L, Li J, Clow F, Goldman J, Zhang L
doi: 10.1016/S1470-2045(26)00282-2
COPD
Effect of maintenance macrolide de-escalation during the Australian summer on exacerbations of obstructive airway diseases: a randomised, double-blind, placebo-controlled trial
Thorax
Thomas D, McDonald V, Wark PA, Pradeepan S, Twaddell S, Gillman A, Hew M, Denton E, Lee J, Chien J, Hinwood M, Harvey ES, Thomas G, Smith A, Arnold D, Gibson PG
doi: 10.1136/thorax-2025-224164