Efficacy of biologic agents in patients with comorbid asthma and chronic rhinosinusitis with nasal polyps: a systematic review and meta-analysis of randomised controlled trials

COMMENTED

Respiratory Tract Infection

Dupilumab versus omalizumab in patients with chronic rhinosinusitis with nasal polyps and coexisting asthma (EVEREST): a multicentre, randomised, double-blind, head-to-head phase 4 trial

★ 3 Recommended by Dr Martin Frey, Faculty Member

★ 3 Recommended and commented by Dr Marcus Hesse, Faculty Member

Lancet Respir Med

De Corso E, Canonica GW, Heffler E, Springer M, Grzegorzek T, Viana M, Horváth Z, Mullol J, Gevaert P, Michel J, Peters AT, Wagenmann M, Zaghloul S, Zhang M, Corbett M, Nash S, Angello JT, Radwan A, Deniz Y, Martin A, Hellings PW

doi: 10.1016/S2213-2600(25)00287-5

COMMENTED

Sleep Apnea

Positive airway pressure therapy and all-cause and cardiovascular mortality in people with obstructive sleep apnoea: a systematic review and meta-analysis of randomised controlled trials and confounder-adjusted, non-randomised controlled studies

★ 3 Recommended and commented by Dr Martin Frey, Faculty Member

★ 0 Recommended and commented by Dr Marcus Hesse, Faculty Member

Lancet Respir Med

Benjafield AV, Pepin JL, Cistulli PA, Wimms A, Lavergne F, Sert Kuniyoshi FH, Munson SH, Schuler B, Reddy Badikol S, Wolfe KC, Willes L, Kelly C, Kendzerska T, Johnson DA, Heinzer R, Lee CH, Malhotra A, medXcloud Group

doi: 10.1016/S2213-2600(25)00002-5

COMMENTED

Cough

Efficacy and safety of twice per year depemokimab in chronic rhinosinusitis with nasal polyps (ANCHOR-1 and ANCHOR-2): phase 3, randomised, double-blind, parallel trials

★ 3 Recommended by Dr Martin Frey, Faculty Member

★ 2 Recommended and commented by Dr Marcus Hesse, Faculty Member

Lancet

Gevaert P, Desrosiers M, Cornet M, Mullol J, De Corso E, Keles Turel N, Maspero J, Fujieda S, Zhang L, Sousa AR, Woods SJ, Davis AM, Schalkwijk S, Edwards D, Ranganathan P, Follows R, Marshall C, Han JK, ANCHOR-1 and ANCHOR-2 trial investigators

doi: 10.1016/S0140-6736(25)00197-7

RECOMMENDED

Asthma

Inflammatory and clinical risk factors for asthma attacks (ORACLE2): a patient-level meta-analysis of control groups of 22 randomised trials

★ 3 Recommended by Dr Martin Frey, Faculty Member

Lancet Respir Med

Meulmeester FL, Mailhot-Larouche S, Celis-Preciado C, Lemaire-Paquette S, Ramakrishnan S, Wechsler ME, Brusselle G, Corren J, Hardy J, Diver SE, Brightling CE, Castro M, Hanania NA, Jackson DJ, Martin N, Laugerud A, Santoro E, Compton C, Hardin ME, Holweg CTJ, Subhashini A, Hinks TSC, Beasley RW, Sont JK, Steyerberg EW, Pavord ID, Couillard S

doi: 10.1016/S2213-2600(25)00037-2

RECOMMENDED

Further Publications

Effect of pulmonary rehabilitation for patients with long COVID-19: a systematic review and meta-analysis of randomized controlled trials

★ 2 Recommended by Dr Martin Frey, Faculty Member

Ther Adv Respir Dis

Li S, Dai B, Hou Y, Zhang L, Liu J, Hou H, Song D, Wang S, Li X, Zhao H, Wang W, Kang J, Tan W

doi: 10.1177/17534666251323482

COMMENTED

COPD

Efficacy and safety of ensifentrine in treatment of COPD: a systematic review and meta-analysis of clinical trials

★ 3 Recommended by Dr Martin Frey, Faculty Member

★ 3 Recommended and commented by Dr Marcus Hesse, Faculty Member

Ther Adv Respir Dis

Hammadeh BM, Younis OM, Alsufi MI, Idrees M, Hussein AM, Aldalati AY, Qtaishat FA, Qatawneh B, Bugazia A, Hamed RA

doi: 10.1177/17534666251347775

RECOMMENDED

Further Publications

Efficacy of respiratory muscle training in improving pulmonary function and survival in patients with amyotrophic lateral sclerosis: a systematic review and meta-analysis

★ 2 Recommended by Dr Martin Frey, Faculty Member

★ 2 Recommended by Dr Marcus Hesse, Faculty Member

Ther Adv Respir Dis

Benzo-Iglesias MJ, Rocamora-Pérez P, Valverde-Martínez MLÁ, García-Luengo AV, Benzo-Iglesias PM, López-Liria R

doi: 10.1177/17534666251346095

COPD

Non-Pharmacological Interventions for Fatigue in Patients with Chronic Obstructive Pulmonary Disease: a Systematic Review and Network Meta-Analysis

Respir Med

Zhang X, Xue J, Chang Y, Zhang R, Zhao J, Li X, Lu H, Jiang X, Yu F, Yang P

doi: 10.1016/j.rmed.2025.108409

Pulmonary Hypertension

Selection of patient-reported outcome measures in pulmonary arterial hypertension clinical trials: a systematic review, meta-analysis and health-related quality of life framework

Eur Respir Rev

Varian F, Burney R, Pearson C, Goh ZM, Newman J, Rawlings G, Zafar H, Kiely DG, Thompson AAR, Condliffe R, Toshner M, McCormack C, Armstrong I, Peasgood T, Carlton J, Rothman AMK

doi: 10.1183/16000617.0006-2025

Related content

Dupilumab versus omalizumab in patients with chronic rhinosinusitis with nasal polyps and coexisting asthma (EVEREST): a multicentre, randomised, double-blind, head-to-head phase 4 trial

Positive airway pressure therapy and all-cause and cardiovascular mortality in people with obstructive sleep apnoea: a systematic review and meta-analysis of randomised controlled trials and confounder-adjusted, non-randomised controlled studies

Efficacy and safety of twice per year depemokimab in chronic rhinosinusitis with nasal polyps (ANCHOR-1 and ANCHOR-2): phase 3, randomised, double-blind, parallel trials

Inflammatory and clinical risk factors for asthma attacks (ORACLE2): a patient-level meta-analysis of control groups of 22 randomised trials

Effect of pulmonary rehabilitation for patients with long COVID-19: a systematic review and meta-analysis of randomized controlled trials

Efficacy and safety of ensifentrine in treatment of COPD: a systematic review and meta-analysis of clinical trials

Efficacy of respiratory muscle training in improving pulmonary function and survival in patients with amyotrophic lateral sclerosis: a systematic review and meta-analysis

Non-Pharmacological Interventions for Fatigue in Patients with Chronic Obstructive Pulmonary Disease: a Systematic Review and Network Meta-Analysis

Selection of patient-reported outcome measures in pulmonary arterial hypertension clinical trials: a systematic review, meta-analysis and health-related quality of life framework