Is Immunotherapy a Contraindication for Treating Lung Cancer Patients with Interstitial Lung Diseases? A Review of the Literature

Lung Cancer

Recommendations for radiotherapy in patients with lung cancer and interstitial lung disease: A Delphi consensus process of the Italian association of radiotherapy and clinical oncology (AIRO)

Lung Cancer

Borghetti P, D'Angelillo R, Facheris G, Borghesi A, Bruni A, Ceruti P, Ferrari K, Filippi AR, Ramella S, Signorelli D, Pappagallo G, Ricardi U, Collaborators

doi: 10.1016/j.lungcan.2025.108807

Interstitial Lung DiseaseLung Cancer

Survival benefit of immune checkpoint inhibitors for non-small cell lung cancer patients with interstitial lung diseases: a nationwide population-based study

Thorax

Karayama M, Miyashita K, Inoue Y, Yasui H, Hozumi H, Suzuki Y, Furuhashi K, Fujisawa T, Enomoto N, Inui N, Suda T

doi: 10.1136/thorax-2025-223430

RECOMMENDED

Lung Cancer

ctDNA can detect minimal residual disease in curative treated non-small cell lung cancer patients using a tumor agnostic approach

★ 1 Recommended by Dr Martin Frey, Faculty Member

★ 1 Recommended by Dr Marcus Hesse, Faculty Member

Lung Cancer

Rosenlund L, Guldbrandsen K, Ahlborn LB, Bloch M, Skougaard K, Albrecht-Beste E, Nellemann HM, Krakauer M, Gørtz PM, Fledelius J, Nielsen AL, Holdgaard PC, Nielsen SS, Grüner JM, Højsgaard A, Petersen RH, Møller LB, Dahl M, Frank MS, Ehlers JH, Saghir Z, Pøhl M, Borissova S, Land LH, Kristiansen C, McCulloch T, Mortensen LS, Christophersen MS, Hilberg O, Rasmussen TL, Simonsen Schwaner SH, Laursen CB, Bodtger U, Lonsdale MN, Meyer CN, Gerke O, Mortensen J, Rasmussen TR, Hjorthaug K, Larsen KR, Meldgaard P, Fischer BM, Sorensen BS

doi: 10.1016/j.lungcan.2025.108528

COMMENTED

Interstitial Lung Disease

ERS/EULAR clinical practice guidelines for connective tissue disease-associated interstitial lung disease. Developed by the task force for connective tissue disease-associated interstitial lung disease of the European Respiratory Society (ERS) and the European Alliance of Associations for Rheumatology (EULAR)Endorsed by the European Reference Network on rare respiratory diseases (ERN-LUNG)

★ 3 Recommended by Dr Martin Frey, Faculty Member

★ 3 Recommended and commented by Dr Marcus Hesse, Faculty Member

Eur Respir J

Antoniou KM, Distler O, Gheorghiu AM, Moor CC, Vikse J, Bizymi N, Galetti I, Brown G, Bargagli E, Allanore Y, Corte TJ, Dieudé P, Cottin V, Fisher BA, Fabre A, Giles JT, Kreuter M, Lundberg IE, Poletti V, Maurer B, Renzoni EA, Müller-Ladner U, Strek ME, Sverzellati N, Studenic P, Mohammed J, Nagavci B, Stamm T, Tonia T, Crestani B, Hoffmann-Vold AM

doi: 10.1183/13993003.02533-2024

Lung Cancer

Prognostic Significance of C-PLAN Index in Patients Treated with Immunotherapy for Non-Small-Cell Lung Cancer

J Clin Med

Nuransoy Cengiz A, Bozkurt O, Cengiz M, Ozkan M, Inanc M, Kefeli U, Cabuk D, Erman M, Kilickap S, Koseci T, Bayir D, Guven DC, Urun M, Cosar R, Sakalar T, Majidova N, Mutlu Ozkan E, Akosman C, Ersoy M, Sahin E, Can Sanci P, Yildiz C, Kolemen E, Agdas G, Kocaaslan E, Turkoğlu E, Yildirim S, Mermit Ercek B, Karakayali A, Arvas H, Kidi MM, Biter S, Yesil Cinkir H, Karahan L, Apaydin Rollas AE

doi: 10.3390/jcm15020642

COMMENTED

Interstitial Lung DiseaseLung Cancer

The 'Liaisons dangereuses' Between Lung Cancer and Interstitial Lung Diseases: A Focus on Acute Exacerbation

★ 3 Recommended and commented by Dr Martin Frey, Faculty Member

★ 1 Recommended by Dr Marcus Hesse, Faculty Member

J Clin Med

Zanini U, Faverio P, Bonfanti V, Falzone M, Cortinovis D, Arcangeli S, Petrella F, Ferrara G, Mura M, Luppi F

doi: 10.3390/jcm13237085

RECOMMENDED

Lung Cancer

Definition of resectable stage III non-small cell lung cancer: A systematic review from EORTC lung cancer group

★ 2 Recommended by Dr Martin Frey, Faculty Member

★ 2 Recommended by Dr Marcus Hesse, Faculty Member

Lung Cancer

Xenophontos E, Giaj Levra N, Durieux V, van Geffen WH, Grisay G, De la Pinta Alonso C, Arasanz H, Prisciandaro E, Ferrara R, Derks J, Von der Thusen J, Dickhoff C, Brandão M, Faivre-Finn C, Edwards J, Ruysscher D, Remon J, Dingemans AC, Berghmans T

doi: 10.1016/j.lungcan.2025.108671

Further Publications

EGFR-mutant lung adenocarcinoma transformed into small cell Lung cancer: A case report and literatures review

Respir Med Case Rep

Chen J, Huang H, Zhong P, Peng S, Zhu X, Ding X, Wang F, Kong P, Song T, Lu Z, Chen L

doi: 10.1016/j.rmcr.2025.102219

Lung Cancer

Associations between Prior Lung Diseases and Risk of Lung Cancer in Populations With No Smoking History: A Systematic Review and Meta-Analysis

Chest

Swami N, Hong JH, Kho S, Kang HM, Chun-Chia Lin L, Ni SC, Florez N, Lan Q, Rothman N, Dee EC, Gomez SL, Cheng I

doi: 10.1016/j.chest.2025.12.034

Related content

Recommendations for radiotherapy in patients with lung cancer and interstitial lung disease: A Delphi consensus process of the Italian association of radiotherapy and clinical oncology (AIRO)

Survival benefit of immune checkpoint inhibitors for non-small cell lung cancer patients with interstitial lung diseases: a nationwide population-based study

ctDNA can detect minimal residual disease in curative treated non-small cell lung cancer patients using a tumor agnostic approach

Prognostic Significance of C-PLAN Index in Patients Treated with Immunotherapy for Non-Small-Cell Lung Cancer

The 'Liaisons dangereuses' Between Lung Cancer and Interstitial Lung Diseases: A Focus on Acute Exacerbation

Definition of resectable stage III non-small cell lung cancer: A systematic review from EORTC lung cancer group

EGFR-mutant lung adenocarcinoma transformed into small cell Lung cancer: A case report and literatures review

Associations between Prior Lung Diseases and Risk of Lung Cancer in Populations With No Smoking History: A Systematic Review and Meta-Analysis