A Metabolomic Signature Predicts Gout Flare Clinical Outcome Associated with Colchicine Prophylaxis

Gout

Colchicine concentrations and relationship with colchicine efficacy and adverse events; post-hoc analysis of a randomised clinical trial of colchicine for gout flare prophylaxis

Arthritis Care Res (Hoboken)

Stamp LK, Horne A, Mihov B, Drake J, Haslett J, Chapman P, Wright DF, Frampton C, Dalbeth N

doi: 10.1002/acr.25548

Gout

The Gout, Hyperuricemia and Crystal-Associated Disease Network (G-CAN) definition of clinical remission in gout

Ann Rheum Dis

Tabi-Amponsah AD, Stewart S, Stamp LK, Taylor WJ, Terkeltaub R, Dalbeth N

doi: 10.1016/j.ard.2025.05.017

Autoimmune Disease

Transcriptomic stratification predicts response to rituximab, abatacept, or the association of hydroxychloroquine and leflunomide in 3 randomised controlled clinical trials of Sjögren's disease

Ann Rheum Dis

Chevet B, Devauchelle-Pensec V, Pontarini E, Baloche V, Bombardieri M, Bowman SJ, Barnes M, Sreih AG, Liu J, Kelly S, Christodoulou A, Moingeon P, Laigle L, Soret P, Le Dantec C, Pers JO, Alarcon-Riquelme ME, Barturen G, Mariette X, van Roon J, Seror R, Nocturne G, Cornec D, Foulquier N, PRECISEADS Clinical Consortium, NECESSITY consortium

doi: 10.1016/j.ard.2025.11.017

Further Publications Rheumatology

Serum Uric Acid Levels in Older Adults: Associations With Clinical Outcomes and Implications for Reference Intervals in Those Aged 70 Years and Over

Arthritis Care Res (Hoboken)

Rickard AJ, Tran C, Schneider HG, Cicuttini FM, Wluka AE, Seeman E, Neumann JT, Karim MN, Zhou Z, Hussain SM, Clark DPQ, Clayton-Chubb D, Tonkin AM, Beilin LJ, Woods RL, McNeil JJ

doi: 10.1002/acr.25621

Allergic Diseases

Clinical Factors Associated With Current Relevance in Allergic Contact Dermatitis: Development of Predictive Models Based on Data From the Spanish Contact Dermatitis Register (REIDAC)

Contact Dermatitis

Pesqué D, Ortiz de Frutos FJ, Navarro-Triviño F, Sanz-Sánchez T, Zaragoza-Ninet V, Córdoba-Guijarro S, Miquel-Miquel J, Silvestre-Salvador JF, González-Pérez R, Ruiz-González I, Mercader-García P, Serra-Baldrich E, Carrascosa-Carrillo JM, Tous-Romero F, Rodríguez-Serna M, Gatica-Ortega ME, Paredes-Suárez C, Pastor-Nieto MA, Chicharro P, Andreu M, Sánchez-Gilo A, Pereyra-Rodríguez JJ, Melé-Ninot G, Sánchez-Pedreño Guillén P, Gómez de la Fuente E, Elosua-González M, Gallardo F, Pujol RM, García-Doval I, Borrego L, Descalzo MÁ, Giménez-Arnau AM

doi: 10.1111/cod.70089

Rheumatoid Arthritis

Clinical and molecular data to predict flares in DMARD optimization in rheumatoid arthritis: a randomised, controlled, open-label, non-inferiority trial

Rheumatology (Oxford)

Blanco FJ, Galindo L, Acasuso B, Balboa-Barreiro V, Cañete JD, Fernández-Gutiérrez B, González-Álvaro I, Álvarez JLP, Bejerano-Herrería C, Silva-Díaz M, Rego-Perez I, Lourido L, Ruiz-Romero C, Uriarte-Ecenarro M, García-Vicuña R, Cuervo A, Ramírez J, Celis R, Rodríguez-Rodríguez L, Abasolo Alcázar L, Nuñez DF, Martín-López M, Toro-Santos FJ, Oreiro N

doi: 10.1093/rheumatology/keag050

Rheumatoid Arthritis

Clinical predictors of flare and drug-free remission in rheumatoid arthritis: preliminary results from the prospective BIO-FLARE experimental medicine study

BMJ Open

Rayner F, Hiu S, Melville A, Bigirumurame T, Anderson A, Dyke B, Kerrigan S, McGucken A, Prichard J, Shahrokhabadi MS, Hilkens CMU, Buckley CD, McInnes IB, Ng WF, Goodyear C, Teare D, Filer A, Siebert S, Raza K, Pratt A, Baker KF, Isaacs J

doi: 10.1136/bmjopen-2024-092478

Gout

Ultrasound-detected crystal depositions and clinical flares dissolve during successful urate-lowering therapy: 5-year follow-up results from the treat-to-target NOR-Gout study

Ann Rheum Dis

Hammer HB, Karoliussen L, Terslev L, Haavardsholm EA, Uhlig T

doi: 10.1016/j.ard.2025.10.029

Rheumatoid Arthritis

Stepwise dose reduction and discontinuation of bDMARD in rheumatoid arthritis: a prospective cohort study of flare-free population, flares, and predictive markers

Arthritis Res Ther

Nozaki Y, Kishimoto K, Tomita D, Itami T, Ashida C, Shiga T, Yamazawa H, Ishimura K, Morimoto Y, Fukuda R, Kinoshita K

doi: 10.1186/s13075-025-03672-y

Related content

Colchicine concentrations and relationship with colchicine efficacy and adverse events; post-hoc analysis of a randomised clinical trial of colchicine for gout flare prophylaxis

The Gout, Hyperuricemia and Crystal-Associated Disease Network (G-CAN) definition of clinical remission in gout

Transcriptomic stratification predicts response to rituximab, abatacept, or the association of hydroxychloroquine and leflunomide in 3 randomised controlled clinical trials of Sjögren's disease

Serum Uric Acid Levels in Older Adults: Associations With Clinical Outcomes and Implications for Reference Intervals in Those Aged 70 Years and Over

Clinical Factors Associated With Current Relevance in Allergic Contact Dermatitis: Development of Predictive Models Based on Data From the Spanish Contact Dermatitis Register (REIDAC)

Clinical and molecular data to predict flares in DMARD optimization in rheumatoid arthritis: a randomised, controlled, open-label, non-inferiority trial

Clinical predictors of flare and drug-free remission in rheumatoid arthritis: preliminary results from the prospective BIO-FLARE experimental medicine study

Ultrasound-detected crystal depositions and clinical flares dissolve during successful urate-lowering therapy: 5-year follow-up results from the treat-to-target NOR-Gout study

Stepwise dose reduction and discontinuation of bDMARD in rheumatoid arthritis: a prospective cohort study of flare-free population, flares, and predictive markers