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Knee arthroplasty compared with joint distraction for osteoarthritis: a phase III randomized controlled trial

Bone Jt Open

Hamilton TW, Lineham B, Stocken DD, Pandit H, KARDS Study Group, Muli A, Kelly R, Collier H, Mujica-Mota R, Metcalfe A, Simpson H, Murray DW, Sharma H, McGonagle D, Ellard DR, Croft J, Stokes J, Harwood P

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Br J Dermatol

Mehta H, Bishnoi A, Parsad D, Kumaran MS, Vinay K

doi: 10.1093/bjd/ljaf306

Melanoma and Skin Cancer

Surgical excision versus topical 5% 5-fluorouracil and photodynamic therapy in the treatment of Bowen's disease: long-term results of a multicenter randomized controlled trial

J Am Acad Dermatol

Moermans MMG, Ahmady S, Nelemans PJ, Arits AHMM, Kessels JPHM, van Pelt HPA, Kelleners-Smeets NWJ, Mosterd K

doi: 10.1016/j.jaad.2025.12.034

Vitiligo

Oral tofacitinib in comparison with dexamethasone oral mini-pulse therapy for the treatment of active nonsegmental vitiligo: A randomized controlled trial

J Am Acad Dermatol

Dev A, Vinay K, Bishnoi A, Kumaran MS, Mehta H, Parsad D

doi: 10.1016/j.jaad.2025.06.006

Rheumatoid Arthritis

Effect of a treatment strategy utilising golimumab, methotrexate and corticosteroids versus methotrexate and corticosteroids in early, untreated psoriatic arthritis (GOLMePsA): a single-centre, double-blind, parallel-group, randomised controlled trial

Lancet Rheumatol

De Marco G, Hensor EMA, Helliwell PS, Sultan S, Dubash SR, Michelena X, Coates LC, Emery P, Tan AL, McGonagle D, Marzo-Ortega H

doi: 10.1016/S2665-9913(25)00156-0

Psoriasis

A Phase 3, Randomized, Double-blind, Active-controlled Clinical Study to Compare BAT2206, a Ustekinumab Biosimilar, with Ustekinumab Reference Product in Patients with Moderate-to-severe Psoriasis: Treatment Period 2 Results (Post Week 28 to Week 52)

J Am Acad Dermatol

Man X, Zaharieva K, Pulka G, Żebrowska A, Deng Y, Mekokishvili L, Yang X, Qi Y, Gu C, Dong Q, Zheng M

doi: 10.1016/j.jaad.2025.08.005

Osteoarthritis

Efficacy of a Very-Low-Calorie Weight Loss Diet Plus Exercise Compared With Exercise Alone on Hip Osteoarthritis Pain : A Randomized Controlled Trial

Ann Intern Med

Hall M, Hinman RS, Knox G, Spiers L, McManus F, De Silva AP, Sumithran P, Harris A, Murphy NJ, Cicuttini F, Hunter DJ, Messier SP, Bennell KL

doi: 10.7326/ANNALS-25-00045

Acne

Bimekizumab demonstrated a favorable safety profile and high levels of efficacy with up to 2 years of treatment in patients with moderate to severe hidradenitis suppurativa: Pooled results from two phase 3 randomized, controlled trials and their open-label extension

J Am Acad Dermatol

Sayed CJ, Kirby B, Garg A, Naik HB, Kimball AB, Zouboulis CC, Jemec GBE, Kokolakis G, Ingram JR, Morita A, Deherder D, Crater C, Rolleri RL, Vaux T, Lambert J, Lukowski B, Bechara FG

doi: 10.1016/j.jaad.2025.11.031

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