Systemic inflammation in gout and the impact of treat-to-target urate-lowering therapy

Gout

Ultrasound-detected crystal depositions and clinical flares dissolve during successful urate-lowering therapy: 5-year follow-up results from the treat-to-target NOR-Gout study

Ann Rheum Dis

Hammer HB, Karoliussen L, Terslev L, Haavardsholm EA, Uhlig T

doi: 10.1016/j.ard.2025.10.029

Gout

Comparative Cardiovascular Safety of NSAID versus Colchicine Use When Initiating Urate-Lowering Therapy Among Patients with Gout: Target Trial Emulations

Arthritis Rheumatol

Yokose C, McCormick N, Lu N, Jiang B, Tan K, Chigurupati S, Rai S, Challener G, Aviña-Zubieta JA, Cipolletta E, Abhishek A, Gaffo A, Januzzi JL, Zhang Y, Choi HK

doi: 10.1002/art.43259

Psoriasis

Residual Inflammation in Patients with Psoriasis Treated with Biologic Therapy: Findings from 3 Prospective Observational Cohorts

J Invest Dermatol

Lecumberri A, Berna-Rico E, Gelfand JM, Svedbom A, Abbad-Jaime de Aragón C, Neria F, Monge D, Ballester-Martínez A, Pindado-Ortega C, Castellanos-González M, Llamas-Velasco M, Barderas MG, Solís J, Fernández-Friera L, Jaén P, Stahle M, Mehta NN, González-Cantero Á

doi: 10.1016/j.jid.2025.03.014

Rheumatoid Arthritis

Prospective study on mental status in rheumatoid arthritis patients on tumour necrosis factor vs non- tumour necrosis factor-targeted therapies after achieving treatment target

Rheumatology (Oxford)

Fujii T, Murata K, Nakabo S, Onishi A, Murakami K, Tanaka M, Morinobu A, Matsuda S

doi: 10.1093/rheumatology/keaf598

Psoriatic Arthritis

Comparative Risk of Infection and Prevalence of Combination Targeted Therapy in Psoriatic Arthritis

JAMA Dermatol

Wu A, Zhang A, Guo Y, Liu J, Yang DM, Chada LP, Ogdie A, Reddy SM, Gottlieb AB, Scher JU, Merola JF

doi: 10.1001/jamadermatol.2025.2980

Rheumatoid Arthritis

Time-independent disease state identification defines distinct trajectories determined by localised vs systemic inflammation in patients with early rheumatoid arthritis

Ann Rheum Dis

Steinz N, Maarseveen TD, van den Akker EB, Cope AP, Isaacs JD, Winkler AR, Huizinga TWJ, Abraham Y, Knevel R

doi: 10.1016/j.ard.2025.04.011

Atopic DermatitisPsoriasis

The 487-gene expression profile test guides systemic therapy selection to improve outcomes for patients with atopic dermatitis: Results from a prospective trial

J Am Acad Dermatol

Silverberg JI, Eichenfield LF, Armstrong AW, Bagel J, Lockshin B, Boh E, Koo J, Farberg AS, Goldberg MS, Quick AP, Lebwohl MG

doi: 10.1016/j.jaad.2026.02.034

Osteoarthritis

The role of sex and systemic inflammation in the development of cardiovascular disease in osteoarthritis: A population-based cohort study using the CLSA

Semin Arthritis Rheum

Perruccio AV, Kral C, Yip C, Eder L, Power JD, Canizares M, Wilfong JM, Heckman G, Badley E

doi: 10.1016/j.semarthrit.2025.152804

Psoriasis

Low-grade systemic inflammation is associated with risk of psoriasis in a general population study of more than 100,000 individuals

Br J Dermatol

Näslund-Koch C, Kvist-Hansen A, Bojesen SE, Skov L, Kobylecki CJ, Vedel-Krogh S

doi: 10.1093/bjd/ljaf147

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