Incidence, Predictors, Management, and Clinical Impact of Major Bleeding Following Left Atrial Appendage Occlusion: The Amulet IDE Randomized Clinical Trial

Atrial Fibrillation

3-Year Clinical Outcomes Comparing the Amulet vs Watchman FLX for Left Atrial Appendage Closure in Patients With Atrial Fibrillation: Results From the SWISS-APERO Randomized Clinical Trial

J Am Coll Cardiol

Galea R, De Marco F, Aminian A, Meneveau N, Chalkou K, Anselme F, Gräni C, Franzone A, Vranckx P, Fischer U, Valgimigli M, Räber L

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Therapy and InterventionFurther Publications

Incidence and Predictors of Persistent Left Atrial Appendage Patency and its Subtypes after Percutaneous Closure: a Pre-Specified Analysis of the SWISS-APERO Trial

Eur Heart J Cardiovasc Imaging

Galea R, Perich Krsnik J, Peters AA, De Marco F, Aminian A, Meneveau N, Heg D, Gräni C, Anselme F, Franzone A, Vranckx P, Fischer U, Bedogni F, Räber L, Valgimigli M

doi: 10.1093/ehjci/jeaf232

Atrial Fibrillation

Left atrial appendage occlusion versus NOACs in patients with atrial fibrillation: Rationale and design of the CATALYST Trial

Am Heart J

Reddy VY, Hylek E, Camm AJ, Halperin JL, Diener HC, Thaler D, Schmidt B, Hara H, Huisman MV, Price MJ, Lakkireddy D, Gage R, Zhao H, Jensen TP, Quintana M, Windecker S

doi: 10.1016/j.ahj.2026.107367

Atrial FibrillationThrombosis and Stroke

Left Atrial Appendage Closure versus Oral Anticoagulation for Stroke Prevention in Atrial Fibrillation: Long-Term Outcomes from Four Randomized Trials

Heart Rhythm

Kaisaier W, Xu Z, Guo L, Dong Y, Chen Y, Lip GYH, Zhu W

doi: 10.1016/j.hrthm.2025.07.051

Atrial Fibrillation

Major Bleeding With Apixaban vs Aspirin: A Subanalysis of the ARTESiA Randomized Clinical Trial

JAMA Cardiol

Siegal DM, Sticherling C, Healey JS, McIntyre WF, Christensen LS, Parkash R, Vanassche T, Conen D, Gold M, Granger CB, Nielsen JC, Carrier M, Wojdyla DM, Erath JW, Rivard L, Kutyifa V, Wright DJ, Lopes RD

doi: 10.1001/jamacardio.2025.4151

Heart, Artery and Coronary DiseasesTherapy and Intervention

Incidence, predictors and clinical impact of upper gastrointestinal bleeding after transcatheter aortic valve replacement

Heart

Nakase M, Draxler DF, Tomii D, Heg D, Okuno T, Samim D, Lanz J, Stortecky S, Reineke D, Windecker S, Pilgrim T

doi: 10.1136/heartjnl-2024-325359

Thrombosis and Stroke

Impact of Peridevice Leak on Clinical Outcomes After Left Atrial Appendage Closure: The OCEAN-LAAC Registry

J Am Heart Assoc

Saito T, Tsuruta H, Kajino A, Iwata J, Sakata S, Ryuzaki T, Sago M, Tanaka S, Chatani R, Hachinohe D, Naganuma T, Ohno Y, Tani T, Okamatsu H, Mizutani K, Watanabe Y, Izumo M, Saji M, Mizuno S, Ueno H, Kubo S, Shirai S, Nakashima M, Asami M, Yamamoto M, Ieda M, Hayashida K, OCEAN‐LAAC investigators

doi: 10.1161/JAHA.125.044422

Atrial FibrillationThrombosis and Stroke

Long-Term Outcomes Following Left Atrial Appendage Occlusion in Medicare Beneficiaries: Outcomes From the National Cardiovascular Data Registry

J Am Heart Assoc

Higgins AY, Zimmerman S, Wang Y, Friedman DJ, Faridi KF, Price MJ, Reddy VY, Holmes DR Jr, Curtis JP, Freeman JV

doi: 10.1161/JAHA.124.039780

Myocardial InfarctionFurther Publications

Low-Dose Rivaroxaban to Prevent Left Ventricular Thrombosis After Anterior Myocardial Infarction: The APERITIF Randomized Clinical Trial

JAMA Cardiol

Puymirat E, Soulat G, Lattuca B, Bouleti C, Delarche N, Roubille F, Cottin Y, Bression D, Combaret N, Gerbaud E, Lhermusier T, Biere L, Dubreuil O, Mousseaux E, Steg PG, Cayla G, Lemesle G, Silvain J, Dillinger JG, Georges JL, Ducrocq G, Genet T, Morelle JF, Montalescot G, Berard L, Rousseau A, Soen M, Simon T, Danchin N, APERITIF study investigators

doi: 10.1001/jamacardio.2026.0026

Related content

3-Year Clinical Outcomes Comparing the Amulet vs Watchman FLX for Left Atrial Appendage Closure in Patients With Atrial Fibrillation: Results From the SWISS-APERO Randomized Clinical Trial

Incidence and Predictors of Persistent Left Atrial Appendage Patency and its Subtypes after Percutaneous Closure: a Pre-Specified Analysis of the SWISS-APERO Trial

Left atrial appendage occlusion versus NOACs in patients with atrial fibrillation: Rationale and design of the CATALYST Trial

Left Atrial Appendage Closure versus Oral Anticoagulation for Stroke Prevention in Atrial Fibrillation: Long-Term Outcomes from Four Randomized Trials

Major Bleeding With Apixaban vs Aspirin: A Subanalysis of the ARTESiA Randomized Clinical Trial

Incidence, predictors and clinical impact of upper gastrointestinal bleeding after transcatheter aortic valve replacement

Impact of Peridevice Leak on Clinical Outcomes After Left Atrial Appendage Closure: The OCEAN-LAAC Registry

Long-Term Outcomes Following Left Atrial Appendage Occlusion in Medicare Beneficiaries: Outcomes From the National Cardiovascular Data Registry

Low-Dose Rivaroxaban to Prevent Left Ventricular Thrombosis After Anterior Myocardial Infarction: The APERITIF Randomized Clinical Trial