Fast intraoperative detection of primary CNS lymphoma and differentiation from common CNS tumors using stimulated Raman histology and deep learning

Central Nervous System Tumors

Streamlined intraoperative brain tumor classification and molecular subtyping in stereotactic biopsies using stimulated Raman histology and deep learning

Clin Cancer Res

Reinecke D, Ruess D, Meissner AK, Fürtjes G, von Spreckelsen N, Ion-Margineau A, Khalid F, Blau T, Stehle T, Al-Shughri A, Büttner R, Goldbrunner R, Ruge MI, Neuschmelting V

doi: 10.1158/1078-0432.CCR-23-3842

Further Publications

Deep Learning Model for Tumor Type Prediction using Targeted Clinical Genomic Sequencing Data

Cancer Discov

Darmofal M, Suman S, Atwal G, Toomey M, Chen JF, Chang JC, Vakiani E, Varghese AM, Balakrishnan Rema A, Syed A, Schultz N, Berger MF, Morris Q

doi: 10.1158/2159-8290.CD-23-0996

Genitourinary Cancer

Cut-offs for relapse detection in men with stage I testicular germ cell tumors during active surveillance within a prospective multicentre cohort study using either raw or housekeeper normalized miR-371a-3p serum levels

Urol Oncol

Fankhauser CD, Wettstein MS, Christiansen AJ, Rothermundt C, Cathomas R, Kaufmann E, Sigg S, Templeton AJ, Hirschi-Blickenstorfer A, Lorch A, Gillessen S, Beyer J, Hermanns T

doi: 10.1016/j.urolonc.2024.07.013

Lymphoma

CAR T-cell therapy induces a high rate of prolonged remission in relapsed primary CNS lymphoma: Real-life results of the LOC network

Am J Hematol

Choquet S, Soussain C, Azar N, Morel V, Metz C, Ursu R, Waultier-Rascalou A, di Blasi R, Houot R, Souchet L, Roos-Weil D, Uzunov M, Quoc SN, Jacque N, Boussen I, Gauthier N, Ouzegdouh M, Blonski M, Campidelli A, Ahle G, Guffroy B, Willems L, Corvilain E, Barrie M, Alcantara M, le Garff-Tavernier M, Psimaras D, Weiss N, Baron M, Bravetti C, Hoang-Xuan K, Davi F, Shor N, Alentorn A, Houillier C

doi: 10.1002/ajh.27316

SABCS 2024

Breast Cancer

CAPItello-291: Comparable prevalence of PIK3CA/AKT1/PTEN alterations in primary and recurrent tumors in HR-positive, HER2-negative breast cancer

Lymphoma

Rapid Tumor DNA Analysis of Cerebrospinal Fluid Accelerates Treatment of Central Nervous System Lymphoma

Blood

Gupta M, Bradley J, Massaad E, Burns E, Georgantas NZ, Maron G, Batten J, Gallagher A, Thierauf J, Nayyar N, Gordon A, Jones S, Pisapia M, Sun Y, Jones PS, Barker FG 2nd, Curry W, Gupta R, Romero J, Wang N, Brastianos P, Martinez-Lage M, Tateishi K, Forst DA, Nahed BV, Batchelor TT, Ritterhouse LL, Iser F, Kessler T, Jordan JT, Dietrich J, Meyerson ML, Cahill DP, Lennerz JK, Carter B, Shankar GM

doi: 10.1182/blood.2024023832

ASH 2024

Lymphoma

A Real-World Comparison of Commercial Use Axi-Cel and Liso-Cel in Patients with Large B-Cell Lymphoma

Leukemia

Real-world patterns and sequences of targeted therapy use in chronic lymphocytic leukemia and small lymphocytic lymphoma in the United States: a longitudinal study

Leuk Lymphoma

Huntington SF, Cheng WY, Sarpong EM, Leng S, Farooqui MZH, Agu US, Catillon M, Lejeune D, Downes N, Matay L, Duh MS, De Nigris E

doi: 10.1080/10428194.2024.2331631

Central Nervous System Tumors

Predicting the risk of neurocognitive decline after brain irradiation in adult patients with a primary brain tumor

Neuro Oncol

Tohidinezhad F, Zegers CML, Vaassen F, Dijkstra J, Anten M, Van Elmpt W, De Ruysscher D, Dekker A, Eekers DBP, Traverso A

doi: 10.1093/neuonc/noae035

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CAR T-cell therapy induces a high rate of prolonged remission in relapsed primary CNS lymphoma: Real-life results of the LOC network

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