High Flow Nasal Oxygen and Low Flow Oxygen Are Equally Effective in Providing Oxygenation During Bronchoscopy Under Conscious Sedation: A Randomised Controlled Trial

COPD

Preventing oxygen desaturation during bronchoscopy in COPD patients using high flow oxygen versus standard management: the randomised controlled PROSA 2 Trial

Eur Respir J

Darie AM, Grize L, Jahn K, Salina A, Röcken J, Herrmann MJ, Pascarella M, Suarez V, Strobel W, Tamm M, Stolz D

doi: 10.1183/13993003.01586-2024

RECOMMENDED

Further Publications

Effectiveness of nasal high-flow oxygen during apnoea on hypoxaemia and intubation success in paediatric emergency and ICU settings: a randomised, controlled, open-label trial

★ 1 Recommended by Dr Martin Frey, Faculty Member

Lancet Respir Med

George S, Williams T, Humphreys S, Atkins T, Tingay D, Gelbart B, Pham T, Craig S, Erickson S, Chavan A, Rasmussen K, Ganeshalingham A, Oberender F, Ganu S, Singhal N, Gibbons K, Le Marsney R, Burren J, Schlapbach LJ, Gannon B, Jones M, Dalziel SR, Schibler A, Paediatric Research in Emergency Departments International Collaborative research networks and the Australian and New Zealand Intensive Care Society Paediatric Study Group

doi: 10.1016/S2213-2600(25)00074-8

COMMENTED

COPD

Nasal High Flow or Noninvasive Ventilation? Navigating Hypercapnic COPD Exacerbation Treatment: A Randomized Noninferiority Clinical Trial

★ 3 Recommended and commented by Dr Martin Frey, Faculty Member

★ 2 Recommended by Dr Marcus Hesse, Faculty Member

Respir Med

Pantazopoulos I, Boutlas S, Mavrovounis G, Papalampidou A, Papagiannakis N, Kontou M, Bibaki E, Athanasiou N, Meletis G, Gourgoulianis K, Zakynthinos S, Ischaki E

doi: 10.1016/j.rmed.2024.107762

COMMENTED

Asthma

Effect of dupilumab on exhaled nitric oxide, mucus plugs, and functional respiratory imaging in patients with type 2 asthma (VESTIGE): a randomised, double-blind, placebo-controlled, phase 4 trial

★ 3 Recommended and commented by Dr Martin Frey, Faculty Member

★ 3 Recommended and commented by Dr Marcus Hesse, Faculty Member

Lancet Respir Med

Castro M, Papi A, Porsbjerg C, Lugogo NL, Brightling CE, González-Barcala FJ, Bourdin A, Ostrovskyy M, Staevska M, Chou PC, Duca L, Pereira AM, Fogarty C, Nadama R, Zhang M, Rodrigues A, Soler X, Sacks HJ, Deniz Y, Rowe PJ, de Prado Gómez L, Jacob-Nara JA

doi: 10.1016/S2213-2600(24)00362-X

COMMENTED

Sleep Apnea

Positive airway pressure therapy and all-cause and cardiovascular mortality in people with obstructive sleep apnoea: a systematic review and meta-analysis of randomised controlled trials and confounder-adjusted, non-randomised controlled studies

★ 3 Recommended and commented by Dr Martin Frey, Faculty Member

★ 0 Recommended and commented by Dr Marcus Hesse, Faculty Member

Lancet Respir Med

Benjafield AV, Pepin JL, Cistulli PA, Wimms A, Lavergne F, Sert Kuniyoshi FH, Munson SH, Schuler B, Reddy Badikol S, Wolfe KC, Willes L, Kelly C, Kendzerska T, Johnson DA, Heinzer R, Lee CH, Malhotra A, medXcloud Group

doi: 10.1016/S2213-2600(25)00002-5

RECOMMENDED

Asthma

Effectiveness of an online asthma education program in adults with asthma in general practice: results from a cluster randomised controlled trial

★ 1 Recommended by Dr Martin Frey, Faculty Member

★ 2 Recommended by Dr Marcus Hesse, Faculty Member

Respir Med

Eck S, Baumgärtel A, Hapfelmeier A, Linde K, Sanftenberg L, Stark S, Schultz K, McClatchey K, Pinnock H, Schneider A, Bavarian Practice-Based Research Network (BayFoNet)

doi: 10.1016/j.rmed.2025.108041

RECOMMENDED

Asthma

Nasal sprays and behavioural interventions compared with usual care for acute respiratory illness in primary care: a randomised, controlled, open-label, parallel-group trial

★ 2 Recommended by Dr Martin Frey, Faculty Member

Lancet Respir Med

Little P, Vennik J, Rumsby K, Stuart B, Becque T, Moore M, Francis N, Hay AD, Verheij T, Bradbury K, Greenwell K, Dennison L, Holt S, Denison-Day J, Ainsworth B, Raftery J, Thomas T, Butler CC, Richards-Hall S, Smith D, Patel H, Williams S, Barnett J, Middleton K, Miller S, Johnson S, Nuttall J, Webley F, Sach T, Yardley L, Geraghty AWA

doi: 10.1016/S2213-2600(24)00140-1

COMMENTED

Further Publications

Submaximal, Low-Dose Eccentric vs Traditional Cycling Exercise: Reduced Oxygen Uptake and Pulmonary Artery Pressure Assessed by Echocardiography in Healthy Middle-aged Adults. A Randomized Controlled, Crossover Trial

★ 3 Recommended and commented by Dr Martin Frey, Faculty Member

Arch Rehabil Res Clin Transl

Müller J, Bauer M, Schneider SR, Mayer L, Titz A, Sturzenegger N, Schwarz EI, Bauer C, Grünig E, Kohler M, Lichtblau M, Ulrich S

doi: 10.1016/j.arrct.2024.100331

Tuberculosis

Effects of conditional cash transfers and pre-test and post-test tuberculosis counselling on patient outcomes and loss to follow-up across the continuum of care in South Africa: a randomised controlled trial

Lancet Infect Dis

Ismail N, Moultrie H, Mwansa-Kambafwile J, Copas A, Izu A, Moyo S, Skinner D, Ismail F, Gosce L, Omar SV, Abubakar I, Madhi SA

doi: 10.1016/S1473-3099(24)00816-8

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Preventing oxygen desaturation during bronchoscopy in COPD patients using high flow oxygen versus standard management: the randomised controlled PROSA 2 Trial

Effectiveness of nasal high-flow oxygen during apnoea on hypoxaemia and intubation success in paediatric emergency and ICU settings: a randomised, controlled, open-label trial

Nasal High Flow or Noninvasive Ventilation? Navigating Hypercapnic COPD Exacerbation Treatment: A Randomized Noninferiority Clinical Trial

Effect of dupilumab on exhaled nitric oxide, mucus plugs, and functional respiratory imaging in patients with type 2 asthma (VESTIGE): a randomised, double-blind, placebo-controlled, phase 4 trial

Positive airway pressure therapy and all-cause and cardiovascular mortality in people with obstructive sleep apnoea: a systematic review and meta-analysis of randomised controlled trials and confounder-adjusted, non-randomised controlled studies

Effectiveness of an online asthma education program in adults with asthma in general practice: results from a cluster randomised controlled trial

Nasal sprays and behavioural interventions compared with usual care for acute respiratory illness in primary care: a randomised, controlled, open-label, parallel-group trial

Submaximal, Low-Dose Eccentric vs Traditional Cycling Exercise: Reduced Oxygen Uptake and Pulmonary Artery Pressure Assessed by Echocardiography in Healthy Middle-aged Adults. A Randomized Controlled, Crossover Trial

Effects of conditional cash transfers and pre-test and post-test tuberculosis counselling on patient outcomes and loss to follow-up across the continuum of care in South Africa: a randomised controlled trial