Autoimmune associated HLAs and T cell autoantigens exhibit common patterns across several autoimmune diseases

Systemic Lupus Erythematosus

Genetic variability associates with ancestry, age at disease onset, organ involvement and disease severity in juvenile-onset systemic lupus erythematosus

Clin Immunol

Natoli V, Charras A, Hasoon MSR, Jorgensen AL, Smith EMD, Gutiérrez EC, Beresford MW, Hedrich CM, UK JSLE Cohort Study Group

doi: 10.1016/j.clim.2025.110540

Systemic Sclerosis

Gastroesophageal reflux disease is associated with a more severe interstitial lung disease in systemic sclerosis in the EUSTAR cohort

Rheumatology (Oxford)

Roth E, Bruni C, Petelytska L, Becker MO, Dobrota R, Jordan S, Mihai C, Muraru S, Carreira PE, De Vries-Bouwstra J, Braun-Moscovici Y, Liakouli V, Moroncini G, Bergmann C, Mouthon L, Denton CP, De Santis M, Cauli A, Adler S, Bernardino V, Truchetet ME, Vonk M, Del Galdo F, Hoffmann-Vold AM, Distler O, Elhai M, EUSTAR collaborators

doi: 10.1093/rheumatology/keaf016

T Cells

BK Virus-Specific T Cell Response Associated with HLA Genotypes, RhD Status, and CMV or EBV Serostatus in Healthy Donors for Optimized Cell Therapy

J Clin Immunol

Mora-Buch R, Tomás-Marín M, Pasamar H, Enrich E, Peña-Gómez C, Rudilla F

doi: 10.1007/s10875-025-01901-2

Further Publications Rheumatology

FGL-1 Modulates Inter-Organ Communication by Controlling T Cell Homeostasis during the Onset of Sjögren's Disease

Arthritis Rheumatol

Otsuka K, Ushio A, Nagao R, Matsuzawa S, Arakaki R, Fukuta K, Mouri Y, Tsunematsu T, Ishimaru N

doi: 10.1002/art.43236

Autoimmune Disease

HLA alleles predisposing to autoimmunity are linked to impaired immunoregulation in patients with juvenile autoimmune liver disease and in their first-degree relatives

J Autoimmun

Wang P, Yuksel M, Gabeta S, Graham J, Hussain M, Blackmore LJ, Huang X, Hadzic D, Samyn M, Grammatikopoulos T, Heneghan M, Liberal R, Longhi MS, Mieli-Vergani G, Vergani D, Ma Y

doi: 10.1016/j.jaut.2025.103436

Psoriasis

Unrestrained MyD88 signaling in A20-deficient keratinocytes triggers T cell dependent Psoriatic Arthritis like disease

J Invest Dermatol

Tobias R, Kumar S, Liu J, Lenci N, Gharabi A, Stibor D, Advincula R, Achacoso P, Huang ZM, Bowman C, Ricardo-Gonzalez R, Nakamura MC, Liao W, Malynn BA, Ma A, Razani B

doi: 10.1016/j.jid.2025.03.043

Autoimmune Disease

A Multicenter Study of Associations between Area-Level Child Opportunity, Initial Disease Severity and Outcomes among Children with Lupus

Arthritis Care Res (Hoboken)

Chang JC, Liu JP, Smitherman EA, Patel PN, Alonzi G, Timmerman L, Morgan GA, deFaria FT, Berbert LM, Weller EA, Costenbader KH, Son MBF

doi: 10.1002/acr.25523

Systemic Lupus Erythematosus

Systemic lupus erythematosus-disease activity score remission and low disease activity were similarly associated with patient-reported outcomes compared with definition of remission in systemic lupus erythematosus remission and lupus low disease activity state

Rheumatology (Oxford)

Nakanishi E, Matsushita M, Minowa K, Tada K, Kawamoto T, Kusaoi M, Amano H, Kon T, Morimoto S, Ikeda K, Suzuki S, Nozawa K, Yang KS, Matsudaira R, Katagiri A, Tsushima H, Urasaki W, Nojiri S, Yamaji K, Tamura N

doi: 10.1093/rheumatology/keaf349

Rheumatoid Arthritis

Rheumatoid arthritis-associated interstitial lung disease in countries across the world

Semin Arthritis Rheum

Heckert SL, Maarseveen TD, Marges ER, Chopra A, Vega-Morales D, Toit RD, Winchow LL, Govind N, Toro-Gutiérrez CE, Knevel R, van der Helm-van Mil AH, Huizinga TW, Allaart CF, Bergstra SA

doi: 10.1016/j.semarthrit.2025.152719

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