Multi-omic profiling reveals immune cell priming signature linked to lupus&#x2009;prognosis

Systemic Lupus Erythematosus

Neutrophil transcriptomics in SLE reveals intrinsic disease signatures, shared ex vivo adaptation, and transcriptional reset after CAR T-cell therapy

Ann Rheum Dis

Dehdashtian E, Hu G, Whiteman L, Islam MT, Gallucci S, Garber M, Borie D, Schett G, Caricchio R

doi: 10.1016/j.ard.2026.02.013

Systemic Lupus Erythematosus

Differential molecular signatures in response to CD19-CAR T cell therapy compared with conventional pharmacotherapy in systemic lupus erythematosus

Ann Rheum Dis

Garantziotis P, Beretta L, Lindblom J, Moysidou GS, Nikolopoulos D, Grieshaber-Bouyer R, Hagen M, Bergmann C, Wirsching A, Bozec A, PRECISESADS Clinical Consortium, Schneider M, Barturen G, Bertsias G, Boumpas DT, Alarcón-Riquelme ME, Mackensen A, Schett G, Parodis I

doi: 10.1016/j.ard.2025.06.2132

Autoimmune Disease

Untargeted breathomics identifies metabolic signatures of immune activity, intestinal integrity, and fatigue in systemic lupus erythematosus

Ann Rheum Dis

Parodis I, Iacubino M, Rocco L, Nikolopoulos D, Palazzo L, Grimmett L, Kerr M, Bellocchi C, Vigone B, Santaniello A, Barturen G, Voskuyl AE, Alarcón-Riquelme ME, Beretta L

doi: 10.1016/j.ard.2025.12.005

Allergic Diseases

Integrated Clinical Trial and Molecular Profiling Reveals Immune Drivers of Chronic Hand Eczema

Allergy

Gery P, Ekren R, Bérard E, Du-Thanh A, Rimet H, Jendoubi F, Lenief V, Raison-Peyron N, Bouznad A, Konstantinou MP, Rioual J, Basso L, Mouiren J, Boussier M, Milpied B, Bulai Livideanu C, Jaulent L, Hacard F, Lefevre MA, Nosbaum A, Seneschal J, Vocanson M, Paul C, Gaudenzio N, Tauber M, French Atopic Dermatitis Network from de GREAT Research group

doi: 10.1111/all.70263

Further Publications Immunology

Daratumumab monotherapy reverses the immune and pro-fibrotic profiles in refractory lupus nephritis patients: a pilot case study

J Autoimmun

Roccatello D, Barinotti A, Radin M, Cecchi I, Rubini E, Mancardi D, Cozzi M, Fenoglio R, Sciascia S

doi: 10.1016/j.jaut.2025.103520

Systemic Lupus Erythematosus

An immunometabolic signature of major depressive disorder in systemic lupus erythematosus

Ann Rheum Dis

Ellul P, Tchitchek N, Kvedaraviciute G, Lorenzon R, Melki I, Delorme R, Rosenzwajg M, Klatzmann D

doi: 10.1016/j.ard.2026.02.019

Psoriatic Arthritis

CD3+ immune cell endotypes are associated with PsA disease phenotype and response to advanced therapy: an integrated mass cytometry and proteomics cohort study

Ann Rheum Dis

Eder L, Dang S, Caucheteux SM, Li X, Thib S, Ganatra D, Ritchlin C, Jurisica I, Piguet V, Diao L, Chandran V

doi: 10.1016/j.ard.2025.10.011

Melanoma and Skin Cancer

Spatial Proteomics of Tertiary Lymphoid Structures Reveals Correlation with Immunotherapy Response in Merkel Cell Carcinoma

Br J Dermatol

Nakamura M, Ogata D, Kato J, Ko YW, Hu J, Yoshimitsu M, Magara T, Kano S, Nakamura R, Kato H, Maekawa T, Yasuda M, Kiniwa Y, Ishikawa H, Nakamura Y, Nagase K, Morita A

doi: 10.1093/bjd/ljaf525

Psoriatic Arthritis

Clonal sharing of CD8+ T-cells links skin and joint inflammation in psoriatic arthritis

Arthritis Rheumatol

Durham LE, Humby F, Ng N, Laddach R, Gray EH, Ryan SE, Steel KJA, Ross R, Povoleri GAM, Nuamah R, Fung K, Kallayil AM, Dhami P, Kirkham BW, Taams LS

doi: 10.1002/art.43286

Dermatology · Immunology · Rheumatology

Multi-omic profiling reveals immune cell priming signature linked to lupus prognosis

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Neutrophil transcriptomics in SLE reveals intrinsic disease signatures, shared ex vivo adaptation, and transcriptional reset after CAR T-cell therapy

Differential molecular signatures in response to CD19-CAR T cell therapy compared with conventional pharmacotherapy in systemic lupus erythematosus

Untargeted breathomics identifies metabolic signatures of immune activity, intestinal integrity, and fatigue in systemic lupus erythematosus

Integrated Clinical Trial and Molecular Profiling Reveals Immune Drivers of Chronic Hand Eczema

Daratumumab monotherapy reverses the immune and pro-fibrotic profiles in refractory lupus nephritis patients: a pilot case study

An immunometabolic signature of major depressive disorder in systemic lupus erythematosus

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