Multi-omic profiling reveals immune cell priming signature linked to lupus&#x2009;prognosis

Systemic Lupus Erythematosus

Differential molecular signatures in response to CD19-CAR T cell therapy compared with conventional pharmacotherapy in systemic lupus erythematosus

Ann Rheum Dis

Garantziotis P, Beretta L, Lindblom J, Moysidou GS, Nikolopoulos D, Grieshaber-Bouyer R, Hagen M, Bergmann C, Wirsching A, Bozec A, PRECISESADS Clinical Consortium, Schneider M, Barturen G, Bertsias G, Boumpas DT, Alarcón-Riquelme ME, Mackensen A, Schett G, Parodis I

doi: 10.1016/j.ard.2025.06.2132

Autoimmune Disease

Untargeted breathomics identifies metabolic signatures of immune activity, intestinal integrity, and fatigue in systemic lupus erythematosus

Ann Rheum Dis

Parodis I, Iacubino M, Rocco L, Nikolopoulos D, Palazzo L, Grimmett L, Kerr M, Bellocchi C, Vigone B, Santaniello A, Barturen G, Voskuyl AE, Alarcón-Riquelme ME, Beretta L

doi: 10.1016/j.ard.2025.12.005

Allergic Diseases

Integrated Clinical Trial and Molecular Profiling Reveals Immune Drivers of Chronic Hand Eczema

Allergy

Gery P, Ekren R, Bérard E, Du-Thanh A, Rimet H, Jendoubi F, Lenief V, Raison-Peyron N, Bouznad A, Konstantinou MP, Rioual J, Basso L, Mouiren J, Boussier M, Milpied B, Bulai Livideanu C, Jaulent L, Hacard F, Lefevre MA, Nosbaum A, Seneschal J, Vocanson M, Paul C, Gaudenzio N, Tauber M, French Atopic Dermatitis Network from de GREAT Research group

doi: 10.1111/all.70263

Further Publications Immunology

Daratumumab monotherapy reverses the immune and pro-fibrotic profiles in refractory lupus nephritis patients: a pilot case study

J Autoimmun

Roccatello D, Barinotti A, Radin M, Cecchi I, Rubini E, Mancardi D, Cozzi M, Fenoglio R, Sciascia S

doi: 10.1016/j.jaut.2025.103520

Psoriatic Arthritis

CD3+ immune cell endotypes are associated with PsA disease phenotype and response to advanced therapy: an integrated mass cytometry and proteomics cohort study

Ann Rheum Dis

Eder L, Dang S, Caucheteux SM, Li X, Thib S, Ganatra D, Ritchlin C, Jurisica I, Piguet V, Diao L, Chandran V

doi: 10.1016/j.ard.2025.10.011

Melanoma and Skin Cancer

Spatial Proteomics of Tertiary Lymphoid Structures Reveals Correlation with Immunotherapy Response in Merkel Cell Carcinoma

Br J Dermatol

Nakamura M, Ogata D, Kato J, Ko YW, Hu J, Yoshimitsu M, Magara T, Kano S, Nakamura R, Kato H, Maekawa T, Yasuda M, Kiniwa Y, Ishikawa H, Nakamura Y, Nagase K, Morita A

doi: 10.1093/bjd/ljaf525

Psoriatic Arthritis

Clonal sharing of CD8+ T-cells links skin and joint inflammation in psoriatic arthritis

Arthritis Rheumatol

Durham LE, Humby F, Ng N, Laddach R, Gray EH, Ryan SE, Steel KJA, Ross R, Povoleri GAM, Nuamah R, Fung K, Kallayil AM, Dhami P, Kirkham BW, Taams LS

doi: 10.1002/art.43286

Systemic Lupus Erythematosus

CD72 downregulation on DN2 B cells associates with disease activity and resistance to rituximab in systemic lupus erythematosus

Rheumatology (Oxford)

Wangriatisak K, Huang W, Sechi G, Oke V, Chemin K, Grönwall C, Gunnarsson I, Malmström V, Faustini F

doi: 10.1093/rheumatology/keag097

T CellsFurther Publications Dermatology

Glioblastoma-instructed astrocytes suppress tumour-specific T cell immunity

Nature

Faust Akl C, Andersen BM, Li Z, Giovannoni F, Diebold M, Sanmarco LM, Kilian M, Fehrenbacher L, Pernin F, Rone JM, Lee HG, Piester G, Kenison JE, Lee JH, Illouz T, Polonio CM, Srun L, Martinez J, Chung EN, Schüle A, Plasencia A, Li L, Ferrara K, Lewandrowski M, Strathdee CA, Lerner L, Quéva C, Clark IC, Deneen B, Lieberman J, Sherr DH, Antel JP, Wheeler MA, Ligon KL, Chiocca EA, Prinz M, Reardon DA, Quintana FJ

doi: 10.1038/s41586-025-08997-x

Dermatology · Immunology · Rheumatology

Multi-omic profiling reveals immune cell priming signature linked to lupus prognosis

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Differential molecular signatures in response to CD19-CAR T cell therapy compared with conventional pharmacotherapy in systemic lupus erythematosus

Untargeted breathomics identifies metabolic signatures of immune activity, intestinal integrity, and fatigue in systemic lupus erythematosus

Integrated Clinical Trial and Molecular Profiling Reveals Immune Drivers of Chronic Hand Eczema

Daratumumab monotherapy reverses the immune and pro-fibrotic profiles in refractory lupus nephritis patients: a pilot case study

CD3+ immune cell endotypes are associated with PsA disease phenotype and response to advanced therapy: an integrated mass cytometry and proteomics cohort study

Spatial Proteomics of Tertiary Lymphoid Structures Reveals Correlation with Immunotherapy Response in Merkel Cell Carcinoma

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