Left Atrial Appendage Closure in Patients Refusing Oral Anticoagulation: The LAAC-REFUSAL Study

Atrial FibrillationThrombosis and Stroke

Left Atrial Appendage Closure versus Oral Anticoagulation for Stroke Prevention in Atrial Fibrillation: Long-Term Outcomes from Four Randomized Trials

Heart Rhythm

Kaisaier W, Xu Z, Guo L, Dong Y, Chen Y, Lip GYH, Zhu W

doi: 10.1016/j.hrthm.2025.07.051

Atrial Fibrillation

3-Year Clinical Outcomes Comparing the Amulet vs Watchman FLX for Left Atrial Appendage Closure in Patients With Atrial Fibrillation: Results From the SWISS-APERO Randomized Clinical Trial

J Am Coll Cardiol

Galea R, De Marco F, Aminian A, Meneveau N, Chalkou K, Anselme F, Gräni C, Franzone A, Vranckx P, Fischer U, Valgimigli M, Räber L

doi: 10.1016/j.jacc.2025.03.535

Atrial FibrillationTherapy and Intervention

Rationale and design of the Anticoagulant Therapy after Left Atrial Appendage Closure (ATLAAC) Trial

Am Heart J

Gosvig K, Goller J, Hansson NH, Brandes A, Modrau I, Rasmussen LF, Eskesen K, Jensen AKG, Belley-Côté E, Whitlock R, Riber LPS

doi: 10.1016/j.ahj.2025.04.015

Thrombosis and Stroke

Impact of Peridevice Leak on Clinical Outcomes After Left Atrial Appendage Closure: The OCEAN-LAAC Registry

J Am Heart Assoc

Saito T, Tsuruta H, Kajino A, Iwata J, Sakata S, Ryuzaki T, Sago M, Tanaka S, Chatani R, Hachinohe D, Naganuma T, Ohno Y, Tani T, Okamatsu H, Mizutani K, Watanabe Y, Izumo M, Saji M, Mizuno S, Ueno H, Kubo S, Shirai S, Nakashima M, Asami M, Yamamoto M, Ieda M, Hayashida K, OCEAN‐LAAC investigators

doi: 10.1161/JAHA.125.044422

Thrombosis and Stroke

Ischemic outcomes after left atrial appendage closure following intracerebral hemorrhage: a retrospective inverse probability weighting analysis from the HANSE-LAAC registry

Clin Res Cardiol

Jurczyk D, Mezger M, Lemmer F, Fatum C, Gradaus R, Drochner-Brocks NK, Saraei R, Frerker C, Stiermaier T, Paitazoglou C, Eitel I

doi: 10.1007/s00392-025-02668-7

Therapy and Intervention

Single versus Dual Antiplatelet Therapy after Left Atrial Appendage Closure: a Propensity Score Matching Analysis

Heart Rhythm

Galea R, Krsnik JP, Bini T, Chalkou K, Gasys A, Brugger N, Madhkour R, Seiffge DJ, Roten L, Siontis GCM, Räber L

doi: 10.1016/j.hrthm.2024.12.007

Therapy and InterventionFurther Publications

Incidence and Predictors of Persistent Left Atrial Appendage Patency and its Subtypes after Percutaneous Closure: a Pre-Specified Analysis of the SWISS-APERO Trial

Eur Heart J Cardiovasc Imaging

Galea R, Perich Krsnik J, Peters AA, De Marco F, Aminian A, Meneveau N, Heg D, Gräni C, Anselme F, Franzone A, Vranckx P, Fischer U, Bedogni F, Räber L, Valgimigli M

doi: 10.1093/ehjci/jeaf232

Atrial Fibrillation

Management of oral anticoagulation after pulsed field ablation for atrial fibrillation: Insights from a multicenter study

Heart Rhythm

Mohanty S, Torlapati PG, Casella M, La Fazia VM, Valeri Y, Gianni C, Al-Ahmad A, Burkhardt JD, Gallinghouse GJ, Horton R, Allison J, Bode W, Di Biase L, Russo AD, Natale A

doi: 10.1016/j.hrthm.2025.03.1952

Atrial Fibrillation

Asundexian or Apixaban in Patients With Atrial Fibrillation According to Prior Oral Anticoagulant Use: A Subgroup Analysis of the OCEANIC-AF Randomized Clinical Trial

JAMA Cardiol

Alexander JH, Lydon EJ, Piccini JP, Viethen T, Oldgren J, Goodman SG, Steffel J, Russo AM, van Gelder IC, Ferdinand KC, Lopes RD, Mundl H, Benczur B, Gómez-Doblas JJ, Glikson M, Goudev A, Grove EL, Halvorsen S, Kiviniemi T, Martin AC, Sandhu RK, Vinereanu D, Rockhold FW, Caso V, Coppolecchia R, Patel MR

doi: 10.1001/jamacardio.2025.0277

Related content

Left Atrial Appendage Closure versus Oral Anticoagulation for Stroke Prevention in Atrial Fibrillation: Long-Term Outcomes from Four Randomized Trials

3-Year Clinical Outcomes Comparing the Amulet vs Watchman FLX for Left Atrial Appendage Closure in Patients With Atrial Fibrillation: Results From the SWISS-APERO Randomized Clinical Trial

Rationale and design of the Anticoagulant Therapy after Left Atrial Appendage Closure (ATLAAC) Trial

Impact of Peridevice Leak on Clinical Outcomes After Left Atrial Appendage Closure: The OCEAN-LAAC Registry

Ischemic outcomes after left atrial appendage closure following intracerebral hemorrhage: a retrospective inverse probability weighting analysis from the HANSE-LAAC registry

Single versus Dual Antiplatelet Therapy after Left Atrial Appendage Closure: a Propensity Score Matching Analysis

Incidence and Predictors of Persistent Left Atrial Appendage Patency and its Subtypes after Percutaneous Closure: a Pre-Specified Analysis of the SWISS-APERO Trial

Management of oral anticoagulation after pulsed field ablation for atrial fibrillation: Insights from a multicenter study

Asundexian or Apixaban in Patients With Atrial Fibrillation According to Prior Oral Anticoagulant Use: A Subgroup Analysis of the OCEANIC-AF Randomized Clinical Trial