Rationale and design of the Anticoagulant Therapy after Left Atrial Appendage Closure (ATLAAC) Trial

Atrial FibrillationThrombosis and Stroke

Left Atrial Appendage Closure versus Oral Anticoagulation for Stroke Prevention in Atrial Fibrillation: Long-Term Outcomes from Four Randomized Trials

Heart Rhythm

Kaisaier W, Xu Z, Guo L, Dong Y, Chen Y, Lip GYH, Zhu W

doi: 10.1016/j.hrthm.2025.07.051

Atrial Fibrillation

3-Year Clinical Outcomes Comparing the Amulet vs Watchman FLX for Left Atrial Appendage Closure in Patients With Atrial Fibrillation: Results From the SWISS-APERO Randomized Clinical Trial

J Am Coll Cardiol

Galea R, De Marco F, Aminian A, Meneveau N, Chalkou K, Anselme F, Gräni C, Franzone A, Vranckx P, Fischer U, Valgimigli M, Räber L

doi: 10.1016/j.jacc.2025.03.535

Therapy and Intervention

Single versus Dual Antiplatelet Therapy after Left Atrial Appendage Closure: a Propensity Score Matching Analysis

Heart Rhythm

Galea R, Krsnik JP, Bini T, Chalkou K, Gasys A, Brugger N, Madhkour R, Seiffge DJ, Roten L, Siontis GCM, Räber L

doi: 10.1016/j.hrthm.2024.12.007

Atrial FibrillationTherapy and Intervention

Left Atrial Appendage Closure in Patients Refusing Oral Anticoagulation: The LAAC-REFUSAL Study

J Am Heart Assoc

Galea R, Bini T, Korsholm K, Sedaghat A, Aminian A, Vij V, Perich Krsnik J, Chalkou K, Siontis G, Roten L, Nielsen-Kudsk JE, Räber L

doi: 10.1161/JAHA.124.040404

Therapy and InterventionFurther Publications

Incidence and Predictors of Persistent Left Atrial Appendage Patency and its Subtypes after Percutaneous Closure: a Pre-Specified Analysis of the SWISS-APERO Trial

Eur Heart J Cardiovasc Imaging

Galea R, Perich Krsnik J, Peters AA, De Marco F, Aminian A, Meneveau N, Heg D, Gräni C, Anselme F, Franzone A, Vranckx P, Fischer U, Bedogni F, Räber L, Valgimigli M

doi: 10.1093/ehjci/jeaf232

Thrombosis and Stroke

Impact of Peridevice Leak on Clinical Outcomes After Left Atrial Appendage Closure: The OCEAN-LAAC Registry

J Am Heart Assoc

Saito T, Tsuruta H, Kajino A, Iwata J, Sakata S, Ryuzaki T, Sago M, Tanaka S, Chatani R, Hachinohe D, Naganuma T, Ohno Y, Tani T, Okamatsu H, Mizutani K, Watanabe Y, Izumo M, Saji M, Mizuno S, Ueno H, Kubo S, Shirai S, Nakashima M, Asami M, Yamamoto M, Ieda M, Hayashida K, OCEAN‐LAAC investigators

doi: 10.1161/JAHA.125.044422

Thrombosis and Stroke

Ischemic outcomes after left atrial appendage closure following intracerebral hemorrhage: a retrospective inverse probability weighting analysis from the HANSE-LAAC registry

Clin Res Cardiol

Jurczyk D, Mezger M, Lemmer F, Fatum C, Gradaus R, Drochner-Brocks NK, Saraei R, Frerker C, Stiermaier T, Paitazoglou C, Eitel I

doi: 10.1007/s00392-025-02668-7

Heart FailureFurther Publications

Randomized investigation of heart failure therapy in patients with advanced cancer at risk of cardiac wasting: Rationale and design of the EMPATICC trial

Eur J Heart Fail

Anker MS, Mahabadi AA, Totzeck M, Tewes M, Mincu R, Khan MS, Butler J, Keller U, Ahn J, Bullinger L, Modest DP, Landmesser U, Lehmann LH, Bercker S, Laufs U, Böhm M, Merkely B, Diek M, Heise T, Hellmich M, Placzek M, Friede T, Anker SD, Rassaf T

doi: 10.1002/ejhf.3799

Atrial FibrillationHeart, Artery and Coronary Diseases

Anticoagulation and Antiplatelet Therapy for Atrial Fibrillation and Stable Coronary Disease: Meta-Analysis of Randomized Trials